Anti Fungal Drugs Flashcards
Mechanism of action of amphotricin
Bind firmly to ergosterol . Of cell membrane
Amphotricen B spectrum
Broad spectrum
The drug of choice for most systemic mycosis
Amphotricin B
Route of amphotricin B
Intravenous for systemic
Locally for treatment cutaneous , mucocutaneous, as lozenges
Type of anemia cuased by Amphotricin B
Normochromic Normocytic anemia
Amphotricin B cuase hypokalemia
T
Anti fungal cuase ms spasm
Amphotrin B
Anti fungal cuase ms spasm
Amphotrin B
Flucytosine mechanism of action
Is converted to 5 fouro uracil which inhibit DNA synthesis
Uses of flucytosine
Systemic infection
Adverse effects flucytosine
Bone marrow depression.
Hepatic dysfunction .
Azoles are broad spectrum
True
Bioavailability of azoles depend on gastric Hcl except
Fluconazole
Bioavailability of azoles depend on gastric Hcl except
Fluconazole
Mechanism of action of azoles
Bind with fungal cell membrane, inhibit …..
By inhibiting …..