Quinine Flashcards
1
Q
When is quinine indicated for use?
A
- Night-time leg cramp
- Plasmodium falciparum malaria
2
Q
What are important adverse reactions of quinines?
A
Can be very toxic
- Tinnitus
- Deafness
- Blindness
- GI upset
- Hypersensitivity
- Prolonged QT interval
- Hypoglycaemia
3
Q
When should quinine be used with caution?
A
- Hearning/visual loss
- First trimester pregnancy
- G6PD deficiency
4
Q
When are quinines contra-indicated for use?
A
- Haemoglobinuria
- Myasthenia gravis
- Optic neuritis
- Tinnitus
5
Q
What drugs can quinine interact with?
A
Drugs that prolong QT interval:
- Amiodarone
- Antipsychotics
- Quinolones
- Macrolides
- SSRIs
6
Q
How should individuals receiving IV quinine be monitored?
A
- Blood glucose
- U+E’s
