QTL mapping Flashcards
trait types:
quantitative and qualitative
quantitative trait loci mapping (QTL)
-quantitative trait loci=polygenetic
-behavior, grwoth, etc
-use DNA markers to find chromosomal regions assoceated with the trait
-try to find genes within identified regions
-positional candidate genes
what are the two kinds of candidate genes
personal candidate genes
functional candidate genes
personal candidate genes
-trait mapped to chromosome region
-gene under investigation resides in this area
-quantitative trait loci (QTL)
functional candidate genes
-function associated with trait
-e.g. appetite pathway and feed intake
DRD4 gene in animals
-mouse (emotional)
-horse (curiosity, vigilance)
-dog (aggression)
candidate gene- leptin
-leptin affects fat deposition in mice
-called the “obese” gene
-involved in appetite regulation
-signal to stop eating
milk production leptin
TT 1.5kg/day higher than CC
why more milk form TT cows
TT enter lactation in better condition