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Infection AM > Pyrexia of unknown origin > Flashcards

Pyrexia of unknown origin Flashcards

1
Q

What are pyrogens?

A

Substances which cause fever

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2
Q

What are the types of pyrexia of unknown origin?

A

Classical
Nosocomial
Neutropenic
HIV associated

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3
Q

What is neutropenic pyrexia?

A

Undiagnosed fever in patient with neutrophils <500/mm3

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4
Q

What are the common causes of HIV associated pyrexia?

A

Mycobacterium TB
Mycobacterium avium
Unknown

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5
Q

What % of pyrexia of unknown cause is infection?

A

<25%

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6
Q

What history should be taken for pyrexia?

A

Travel
Occupation and hobbies
PMH
Dryg history

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7
Q

What are the initial investigations for pyrexia of unknown cause?

A 
FBC
Blood culture
CRP and ESR
Urinalysis and urine microscopy
CXR
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8
Q

What investigations would be indicated if there is a history of tropical travel?

A

Bloods
HIV
Bone marrow

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9
Q

What investigations would be indicated if there is a new murmur?

A

Echo

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10
Q

What investigations would be indicated if there are headaches?

A

Temporal artery biopsy

CT PET

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11
Q

What investigations would be indicated if there is microhaematuria?

A

Autoantibodies +/- renal biopsy

Renal US

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12
Q

What investigations would be indicated if there is TB contact?

A

Sputum

Bone marrow

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13
Q

What investigations would be indicated if there is drug misuse?

A

Screen for blood borne viruses

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14
Q

What is the treatment of pyrexia of unknown origin?

A

Treat cause i it can be found
-TB=chemo
-temporal arteritis= steroids
Some types responsive to NSAIDs

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15
Q

What is the most common outcome of pyrexia in the young?

A

Spontaneous resolution

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16
Q

What is fabricated fever?

A

Fever real but self induced

Psych referral

Infection AM (11 decks)

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