Pulmonology Flashcards

1
Q

Duration of chronic cough

A

> 8 weeks

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2
Q

First step in evaluation of a chronic cough

A

Chest xray

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3
Q

Most common causes of chronic cough in a non-smoker, not on ACEIs, with normal PE and CXR: (3)

A
  1. Postnasal drip
  2. Asthma
  3. GERD
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4
Q

Criteria for diagnosis of Bronchial Asthma on spirometry:

A

Low FEV1
FEV1/FVC ratio is <0.7
FEV1 is increased by >12% and 200mL post bronchodilator
FEV1 is increased by >12% and 200mL from baseline after 4 weeks on steroid trial

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5
Q

Best diagnostic test in COPD during acute exacerbations

A

ABG

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6
Q

Major site of increated resistance in most individuals with COPD

A

Small airways (<2mm)

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7
Q

Most important prognostic factor for COPD

A

Degree of airflow obstruction

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8
Q

When do you start supplemental O2 in COPD?

A

pO2 <55/ sat 88%

or pO2 <60/sat 90% if with signs of pulmonary hypertension or lung failure

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9
Q

PDE4 inhibitor that may be beneficial for COPD

A

Roflumilast

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10
Q

Target O2 sat in acute exacerbations of COPD:

A

%>=90

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11
Q

Bacteria commonly implicated in COPD exacerbation:

A

H. influenzae
M. catarrhalis
S. pneumoniae

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12
Q

In CAP, gross hemoptysis is suggestive of:

A

CA-MRSA

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13
Q

Chest radiograph in CAP will resolve at around:

A

4-12 weeks

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14
Q

Primary lung abscesses are usually due to:

A

Aspiration

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15
Q

Recommended treatment for primary lung abscess

A

Clindamycin IV or

Beta lactam with BLIC IV

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16
Q

Lung zones most commonly involved in primary PTB

A

Middle and lower lung zones

17
Q

Lung zones most commonly involved in post-primary PTB

A

Apical and posterior segments of upper lobes

Superior segments of lower lobes

18
Q

Target MAP for septic shock

A

65 mmHg

19
Q

PaO2/FiO2 ratio idicative of ARDS

A

<300

20
Q

These cause DIRECT lung injury which may lead to ARDS: (5)

A
Pneumonia
Aspiration
Pulmonary contusion
Near-drowning
Toxic inhalation
21
Q

After starting controller therapy for asthma, physician should monitor response after:

A

2-3 months

22
Q

Serum and pleural fluid protein gradient >___g/L suggests transudative pleural effusion

A

31 g/L

23
Q

Most common cause of pleural effusion

A

LV failure

24
Q

Pleural effusion: factors that suggest need for more invasive procedure than thoracentesis (in increasing order of importance) (5)

A
Loculated pleural fluid
Pleural fluid pH <7.20
Pleural fluid glucose <60 mg/dL
Positive gram stain or culture of pleural fluid
Presence of gross puss
25
Q

Initial recommended therapy for primary spontaneous pneumothorax

A

Simple aspiration

26
Q

Most secondary pneumothorax is due to:

A

COPD

27
Q

The major risk factor for asthma

A

Atopy

28
Q

The characteristic physiologic abnormality in asthma

A

Airway hyperresponsiveness

29
Q

If pleural effusion is clinically transudative but biochemically exudative, check________

A

Serum-pleural fluid gradient

>31 g/dL is transudative

30
Q

This is the most highly significant predictor of FEV1 in COPD

A

Pack-years of smoking

31
Q

Ventilatory failure is defined as PCO2>____mmHg

A

PCO2>45mmHg

32
Q

Single strongest predictor of COPD exacerbations

A

Previous exacerbation