GIT Flashcards

1
Q

Acute LGIB w/ hemodynamic instability: after initial resuscitation, what is the next diagnostic step?

A

Upper endoscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

UGIB: Change in hemoglobin may not be evident up to ____ hours after bleeding event

A

72 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Most frequent PE finding of GU or DU

A

Epigastric tenderness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

First step in a patient with new onset dyspepsia <40 y/o and without alarm symptoms

A

Non-invasive H. pylori testing

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Melena is blood that has been in the GIT for at least _____ hours

A

14 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Gold standard of H. pylori testing

A

Histologic evaluation of endoscopic biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Scleral icterus means bilirubin is >___ mg/dL

A

3

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Best way to initially assess GIB

A

BP and HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most reliable marker of severity of liver disease and it’s hallmark symptom

A

Jaundice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Single most common risk factor for hep C infection:

A

Injection drug use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Often the only clinical finding in alcholic liver disease

A

Hepatomegaly

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Treatment of ALD with severe hepatitis, discriminant function >32 or MELD >20

A

Steroids (Prednisolone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Components of MELD

A

Bilriubin, INR, Creatinine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Medical management for portal hypertension

A
Nonselective beta blockers
Splanchnic vasoconstrictors (Somatostatin, octreotide)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Chylous ascites indicates a TG level of

A

> 200 mg/dL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Remains the gold standard of determining cause of ascites

A

Laparotomy/laparoscopy with peritoneal biopsy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Patients with small amounts of ascites can be initially managed by:

A

Sodium restriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Moderate amounts of ascites are managed with:

A

Diuretics (initially spironolactone)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Management for refractory ascites

A

Repeated large volume paracentesis and TIPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

In colonic adenoCA, obstruction here leads to hematochezia, narrowing of stool caliber, tenesmus

A

Rectosigmoid area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Colon CA: Best predictor of long-term prognosis

A

Pathologic stage at diagnosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Urgent endoscopy is recommended in cirrhotics with UGIB within how many hours?

A

12 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Single best acute measure of hepatic synthetic function

A

Coagulation studies

24
Q

Earliest radiologic change in ulcerative colitis

A

Fine granular changes

25
Q

Earliest macroscopic finding in Crohn’s disease

A

Aphthous ulcers

26
Q

Defining lesions of UC

A

Crypt abscesses and ulcers

27
Q

Treatment of SBP

A

Cefotaxime/Ofloxacin/Ciprofloxacin + IV Albumin

28
Q

Cornerstone of therapy in dumping syndrome

A

Dietary modificiation

29
Q

Treatment of choice for stress prophylaxis

A

PPIs

30
Q

The two principal gastric secretory products that induce mucosal injury

A

HCl and Pepsinogen

31
Q

In pancreatitis, lipase stays elevated for _____ days

A

7-14 days

32
Q

Most important clinical finding in regard to severity of the acute pancreatitis episode

A

Persistent organ failure >48h

33
Q

Initial imaging modality of choice for acute pancreatitis

A

Abdominal ultrasound

34
Q

Patients with gallstone pancreatitis with signs of acute cholangitis should undergo _____ within 24-48 hrs

A

ERCP

35
Q

Most common cause of chronic pancreatitis in the USA

A

Alcoholism

36
Q

Test with the best sensitivity and specificity for chronic pancreatitis

A

Secretin test

Becomes abnormal when 60% or more of the exocrine pancreas has been lost

37
Q

Diffuse calcifications noted on plain film the of the abdomen are pathognomonic for:

A

Chronic pancreatitis

38
Q

Cornerstone of therapy in chronic pancreatitis

A

Pancreatic enzyme replacement

39
Q

Most common congenital anatomical variant of the human pancreas

A

Pancreas divisum

40
Q

Most common histologic response to hepatotoxic stimuli

A

Fatty liver

41
Q

Cornerstone of treatment of alcoholic liver disease

A

Complete abstinence

42
Q

Most common cause of ascites

A

Portal hypertension

43
Q

Nutritional vitamin D deficiency is best assessed by obtaining serum ________

A

Serum 25-hydroxyvitamin D

44
Q

Most common site of inflammation in Crohn’s disease

A

Ileum

45
Q

Most common gastrointestinal cause of hypernatremia

A

Diarrhea

46
Q

Pneumococcal vaccine should be administered 2 weeks [before/after] splenectomy

A

2 weeks before splenectomy

47
Q

Usually the first indicator of portal hypertension

A

Hypersplenism

48
Q

Perhaps the most reliable physical finding in the liver examination

A

Hepatic tenderness

49
Q

Most common symptoms in Hep C

A

Fatigue

50
Q

Most important factor in progression of Hep B into cirrhosis and HCCA

A

Level of HBV replication

51
Q

Best therapy for hepatorenal syndrome

A

Liver transplant

52
Q

Acetaminophen dose associated with fatal fulminant liver disease

A

25g and above

53
Q

Most distinguishing serologic feature of chronic hep D

A

Anti-LKM3

54
Q

Best prognostic factor in chronic Hep C

A

Liver histology

55
Q

Mainstay of treatment of autoimmune hepatitis

A

Glucocorticoids