Pulmonary Vascular Disease Flashcards

1
Q

What 2 diseases does this topic cover?

A

Pulmonary embolism and hypertension

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2
Q

What is a pulmonary embolism and how does it arise?

A

A thrombus usually forms in deep veins (DVT) and embolises to the pulmonary arteries

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3
Q

Risk factors for developing a venous thromboembolism?

A
Trauma
Cancer
Cardiopulmonary disease
Pregnancy
Inherited thrombophilia
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4
Q

Symptoms of a Pulmonary Embolism?

A

Pleuritic chest pain
Acute dyspnoea
Pyrexia

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5
Q

Signs on examination?

A

Tachycardia and tachypnoea
Hypoxia
Hypotension - Syncopes

Stoney dullness to percusion

Pleural rub heard

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6
Q

List some investigations that are done for a PE?

A
FBC, Us an Es, D-Dimers
Blood gases - reduced PaO2 and PaCO2
CxR
ECG
CT pulmonary angiogram
Echos
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7
Q

Treatment for a PE?

A
LMWH
Warfarin
Oral anticoagulants
Thrombolysis
Pulmonary embolectomy
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8
Q

What is pulmonary hypertension?

A

Mean pulmonary artery pressure of over 25mmHg

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9
Q

What 2 types of P.HT is there and how common are they?

A

Primary - rare

Secondary - common especially in elderly - due to underlying disease

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10
Q

What happens if P.HT is left untreated?

A

P.HT is rapidly progressive and death can occur

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11
Q

Symptoms of P.HT?

A

Dyspnoea
Chest pain
Syncope

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12
Q

Signs of P.HT?

A

Elevated JVP
RV heave
Hepatomegaly
Ankle oedema

Loud pulmonary 2nd heart sound

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13
Q

Invesigations for P.HT?

A
ECGs
CxR
Echos
V/Q scans
Right heart caths
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14
Q

What does a right heart cath measure in P.HT?

A

Pulmonary artery pressure
Wedge pressure
CO

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15
Q

General treatment for P.HT?

A

Treat the underlying condition - O2, anticoagulants, diuretics

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16
Q

Specific treatment for P.HT?

A

CCBs - amlopidine (vasodilating)

Prostacyclin

Endothelial receptor antagonists

Phosphodiesterase inhibitors

17
Q

Other treatments for P.HT - surgical?

A

Thrombo-endarter-ectomy - removes clot

Lung/heart transplants