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Respiratory > Pulmonary fibrosis > Flashcards

Pulmonary fibrosis Flashcards

1
Q

what is fibrosis?

what causes too much fibrosis generally speaking?

A

scarring of healthy tissue

too much inflammation

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2
Q

fibrosis is scarring, what is this scar made of mainly and what cell dumps this material?

A

collagen

fibroblasts

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3
Q

Risk factors for Pulmonary fibrosis?

-5

A 
Old 
Male 2x
Smoker 
FHx 
Dust exposure
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4
Q

Idiopathic pulmonary fibrosis effects which zone of lungs?

A

Lower

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5
Q

CF , TB & Sarcoidosis effects which zone of lungs?

A

upper

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6
Q

Asbestos & radiation effects which zone of lungs?

A

Lower

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7
Q

Complications of pulmonary fibrosis?

-3 main ones

A

Lung Cancer
Pulmonary HTN
cor pulmonale

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8
Q

symptoms of idiopathic pulmonary fibrosis?

-3

A

SOB – progressive
dry cough
Malaise

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9
Q

you auscultate pt with idiopathic pulmonary fibrosis, what do you hear?

which zone do you hear it in?

A

Basal fine end-inspiratory crackles

lower zones

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10
Q

gold.S Ix for idiopathic pulmonary fibrosis?

positive finding?
-1

A

CT

honeycombing

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11
Q

spirometry of pt with idiopathic pulmonary fibrosis:
what is the pattern?
what decreases the most?

A

restrictive

↓↓↓FVC

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12
Q

prognosis of idiopathic pulmonary fibrosis:

most die in 3 years

most die in 15 years

which is more accurate?

A

most die in 3 years

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13
Q

which drugs can be used for idiopathic pulmonary fibrosis:

  • give names example of drugs? (2)
  • group of these drugs?
A

Pirfenidone or nintedanib

Anti-fibrotic agents

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14
Q

Supportive Mx for idiopathic pulmonary fibrosis?

-3

A

Pulmonary Rehab
LTOT
Vaccinate against pneumococcus & influenza

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15
Q

last line Mx for idiopathic pulmonary fibrosis?

A

Lung transplant

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16
Q

on bloods which antibody is found in 30% of those with IPF?

A

Antinuclear antibodies

17
Q

on bloods which factor is found in 20% of those with IPF?

A

rheumatoid factor

Respiratory (22 decks)

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