Pulmonary Embolism Flashcards

1
Q

Pulmonary Embolism

A

Block of pulmonary artery by a blood clot, fat, tumour or air.

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2
Q

How does PE cause pulmonary infarction?

A

Blood flow & oxygen supply to lung tissues is compromised => lung tissue may die.

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3
Q

Cause

A

Usually arise from DVT in pelvis or legs

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4
Q

How does DVT cause PE

A

Clots break off & pass through veins & right side of the heart.

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5
Q

Classification ation

A

Massive (with shock or syncope), Major (with RV dysfunction), Major (with normal RV function), Minor.

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6
Q

DVT Classification ficaion

A

Proximal (Ile-femoral) & distal (popliteal)

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7
Q

Proximal (Ileo-Femoral)

A

Most likely to embolise & lead to chronic venous insufficiency & venous lung ulcers.

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8
Q

What DVT is more likely to embolise

A

Proximal: Ileo-femoral.

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9
Q

Risk Factors

A

Surgery, immobility (long-haul flight), oral contraceptive, pregnancy, pelvic obstruction, trauma, thrombophilia, malignancy, obesity, pulmonary hypertension, IV drug users, vascularise.

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10
Q

Virchow ‘s Triad

A
  1. Factors in vessel wall.
  2. Abnormal blood flow.
  3. Hypercoagulable blood.
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11
Q

Side effects of anticoagulants

A

Increased risk of bleeding.

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12
Q

Symptoms: General

A

Acute SOB, collapse, pleuritic, chest pain, haemoptysis, sudden death.

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13
Q

Signs: General

A

Tachycardia, tachypnoea, cyanosis, fever, low BP, crackles, pleural rub, signs of pleural effusion.

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14
Q

Symptoms/Signs: Large

A

CV shock, low BP, central cyanosis, sudden death, sustained systolic <90, sever hypoxaemia.

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15
Q

Symptoms/Signs: Medium

A

Pleuritic pain, haemoptysis, dyspnoea

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16
Q

Symptoms/Signs: Small/Recurrent

A

Progressive dyspnoea, pulmonary hypertension, right heart failure.

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17
Q

Symptoms: DVT

A

Whole leg or calf swollen, red, hot and tender.

18
Q

Investigations: PE

A

CXR, ECG, D-diners, Isotope lung scan, CTPA, Perfusion (Q) scan, ABGs

19
Q

Investigations: DVT

A

ultrasound Doppler leg scan, CT scan.

20
Q

Early CXR

A

Normal

21
Q

Later CXR

A

Basal atelectasis, consolidation & pleural effusion.

22
Q

ECG

A

Acute right heart strain pattern & acute dilatation of RV.

23
Q

D-dimers

A

Usually raised

24
Q

Isotope lung scan

A

Sensitive for small peripheral embol, perfusion defect before infarction, V/Q matched defect after infarction.

25
Q

When should a Perfusion (Q) scan used

A

If pregnant

26
Q

ABGs

A

Decreased PaO2 & SaO2, type I Resp failure, Resp alkalosis

27
Q

Management of low risk

A

Ambulatory pathway -> home

28
Q

Management of high risk

A

BP Monitoring & MHDU.

29
Q

Management of intermediate high risk

A

Ward or MHDU

30
Q

Should you provide treatment before test results in low suspicion PE?

A

Wait for results.

31
Q

Should you provide treatment before test results in moderate suspicion PE?

A

Weigh pros & cons

32
Q

Should you provide treatment before test results in high suspicion PE?

A

Empirical treatment

33
Q

Treatment for DVT/PE

A

Thrombo-embolectomy, intra-catheter directed thrombolysis, EKOS.

34
Q

Treatment of Massive PE

A

Thrombolysis or surgery

35
Q

Treatment of Major PE (with RV dysfunction)

A

Anticoagulants & thrombolysis

36
Q

Major PE (Without RV dysfunction)

A

O2, thrombolysis, anticoagulants.

37
Q

Prevention of DVT

A

Early post-op mobilisation, TED compression stockings, calf muscle exercises, subcutaneous low dose mol weight heparin peri-operatives, DOAC, IVC filter to prevent embolisation from ileofemoral clot.

38
Q

Duration of Treatment for unprovoked PE

A

6 months

39
Q

Duration of Treatment for provoked PE

A

3 months

40
Q

Duration of Treatment of unprovoked low-risk PE

A

3 months

41
Q

Duration of treatment of high risk proximal DVT

A

6 months

42
Q

Duration of treatment of recurrent PE

A

Life-long.