Interstitial Lung Disease

Question 1

Interstitial Lung Disease

Answer 1

Any lung disease that diffuse lay affects the interstitium/lung parenchyma. Characterised by chronic inflammation & progressive interstitial fibrosis.

Question 2

Is ILD restrictive or obstructive?

Answer 2

Restrictive lung pattern

Question 3

Interstitium

Answer 3

Alveoli & terminal bronchi

Question 4

Lung parenchyma

Answer 4

Portion of lung involved in gas transfer.

Question 5

Does ILD interfere with gas transfer?

Answer 5

Yes

Question 6

Early stage

Answer 6

Alveolitis

Question 7

Alveolitis

Answer 7

Injury with inflammatory cell infiltration

Question 8

Acute

Answer 8

Exemplified by ARDS

Question 9

Conditions associated with upper zone fibrosis

Answer 9

Hypersensitivity Pneumonitis, sarcoidosis, TB.

Question 10

Conditions associated with mid zone fibrosis

Answer 10

Progressive massive fibrosis

Question 11

Conditions associated with lower zone fibrosis

Answer 11

IPF, Asbestosis, Rheumatoid Arthiritis, Amiodarone

Question 12

Known Causes

Answer 12

Occupational, drugs, hypersensitivity, infections.

Question 13

ILDS with occupational causes

Answer 13

Asbestosis, silicosis.

Question 14

ILDS with hypersensitivity

Answer 14

Hypersensitivity pneumonitis

Question 15

ILDS with infections

Answer 15

TB

Question 16

ILDS with systemic causes

Answer 16

Sarcoidosis, ulcerative colitis, autoimmune thyroid disease.

Question 17

Idiopathic ILDs

Answer 17

IPF & connective tissue diseases.

Question 18

Symptoms

Answer 18

Dyspnoea, dry cough

Question 19

Investigations

Answer 19

CXR, biopsy (transbronchial & thoracoscopic)

Question 20

CXR

Answer 20

Ground glass appearance in lungs