Anatomy Flashcards
Upper Respiratory Tract
Nasal cavities, oral cavity, pharynx, larynx
Lower Respiratory Tract
Trachea, right & left main bronchus, lobar bronchi, segmental bronchi, bronchioles, alveoli
Where does the larynx become the trachea?
At the level of C6 verterbrae
Where does the pharynx become the oesophagus?
At the level of C6 verterbrae.
Lobar Bronchi
1 lobar bronchus for each of the 5 lung lobes.
Segmental Bronchi
1 segmental bronchus for each of the 10 bronchopulmonary segments
Lobes of the right lung
Upper, middle and lower
Lobes of the left lung
Upper and lower
Lung lobe
Area of the lung that each lobar bronchi supply with air
Bronchopulmonary segement
Area of lung lobe that each segmental bronchi supply with air
Fissures
Deep crevices that separate the lobes from each other
Lining on inside of bronchial tree (except for distal bronchioles & alveoli)
Respiratory epithelium
Respiratory Epithelium
Contain:
- Mucous glands secrete mucous onto epithelial surface.
- Cilia beat to sweep mucous + any foreign bodies stuck in the mucous superiorly, toward the pharynx.
Mucociliary Escalator
Cilia beat to sweep mucous _ any foreign bodies stuck in the mucous superiorly, toward the pharynx.
What interferes with normal beating of cilia?
Cooling/drying of mucosa & toxins in cigarette smoke.
Hyaline cartilage
Supports the walls of the trachea & all the bronchi & assists with maintaining airway patency
Do alveoli have cartilage?
No
Do alveoli have smooth muscle?
No
Why don’t alveoli have smooth muscle or cartilage?
Alveolar walls have to be extremely thin as smooth muscle and cartilage would impact on diffusion.
Cartilage in the respiratory tree
Cartilage gradually reduces distally in the respiratory tree
Smooth muscle in the respiratory tree
Smooth muscle becomes progressively more prominent distally in the respiratory tree
Bronchioles: smooth muscle
Smooth muscle is the most prominent feature of bronchioles => bronchioles can constrict or dilate
Requirements for gas transfer between air in alveoli & blood in pulmonary capillaries
- Sufficient functioning lung tissue.
- Sufficient O2 in inspired air.
- No CO2 in inspired air.
- Minimal thickness of walls of alveoli.
- Minimal tissue fluid in tissue spaces around the alveolar capillaries.
Dangers to respiratory tract
- Resp tract may become narrowed: Bronchiole constriction, swelling of mucosa/overproduction of mucous, growing tumour may compress tract.
- Foreign bodies being inhaled into resp tract.
What separates the 2 nasal cavities
Nasal septum
Nasal septum
- Bony Part (Posterior): Ethmoid bone & vomer.
- Cartilaginous Part (Anterior)
Skeleton of larynx
Epiglottis, thyroid cartilage, cricoid cartilage, 2 arytenoid cartilages
Functions of larynx
- Cartilages help to maintain patency of URT.
- Helps prevent entry of foreign bodies into the LRT (vocal cords)
- Produces sounds (vocal sounds)
Trachea
Inferior continuation of larynx
Narrowest part of the larynx
Rima glottidis
Function of Vocal cords
- Airway protection.
2. Voice production
Voice Production
- Phonation: Expire air across vocal cords, cords vibrate to produce sound.
- Articulation: Sound is modified in nose or mouth to produce vowels and consonants.
Airway Protection by Vocal Cords
Vocal cords can approximate in the midline, closing the rima Glottidis & preventing a foreign body inhaled into the trachea => stimulates cough reflex to expel foreign body via pharynx and oral cavity.
Heimlich manoeuvre
Raises abdominal pressure, forces diaphragm superiorly, raises pressure in chest & lungs, forces air from lungs into trachea, forces air through rima glottidis to expel foreign body out of URT.
Dangers of breathing in cold/dry air
Cooling & drying out of respiratory tract => damages the mucocili]ary escalator & predisposes to infection.
Dangers of breathing in unclean air
Breathing in infected foreign bodies or bacteria/viruses etc. => infection.
How do we warm air?
Respiratory mucosa lining the walls of the nasal cavities has a very good arterial blood supply providing warmth
How to de humidity air?
Respiratory mucosa produces mucous providing moisture
How do we clean air?
Sticky mucous traps potentially infected particles & tonsils produce white blood cells in defence against infection.
Chest wall
- Skin & Fascia.
- Bones.
- Skeletal muscles.
- Diaphragm.
- Parietal pleura.
Thoracic Skeleton
- 12 Pairs of Ribs (True 1-7, False 8-10, Floating 11-12)
- Intercostal spaces
- Costal margin.
- 12 thoracic vertebrae.
- clavicle & scapula
- sternum
Bones of chest wall
- Sternoclavicular joint.
- Sternocostal articulation with costal cartilage of rib 1
- Manubrium
- Sternal angle (at level of rib 2)
- Body
— Xiphoid process
Joints of thoracic skeleton
Sternocostal joints & costochondral joints
Sternocostal joints
Synovial
Costovertebral joints
Limited movement at these joints
Muscles of breathing
- Intercostal muscles: make chest wall expand during breathing by pulling adjacent ribs upwards and outwards.
- Diaphragm.
Intercostal muscles
3 layers of skeletal muscles are located between ribs in intercostal spaces:
- external intercostal muscles.
- Internal intercostal muscles.
- innermost intercostal muscles.
Parietal pleura
Internal lining of the chest wall
Visceral pleura
Skin attached lung lobes
Pleural cavity
Space that surrounds the lung in 3D apart from where main bronchus enters it
- Between parietal & visceral layers of pleura
At level of C6 vertebrae
Larynx becomes trachea & pharynx becomes oesophagus.
Where can you palpate the trachea
At the jugular notch of the manubrium
Isthmus of thyroid gland
Anterior to tracheal cartilages 2-4.
2 parts of Thorax
Chest walls & chest cavity
Function of chest walls
- Protect heart & lungs.
- Make movements of breathing.
- Breast tissue: lactation.
Chest cavity
Within chest wall, consists of mediastinum & right & left pleural cavities, contains vital organs, major vessels and nerves.
Lung development
Embryo: Lung bud pushes out from mediastinum, covered in pleura.
Adults: Pleural cavity: potential space, pleural fluid.
Both: Parietal pleura on wall, visceral pleura on lungs, reflect at lung roots.
Pleural fluid
Lubricant that provides surface tension - secreted by pleurae into pleural cavity.
Intercostal spaces
11 pairs, each carrying a neuro-vascular bundle between internal and innermost intercostal muscle layers.
Diaphragm
- Forms floor of chest cavity & roof of abdominal cavity.
- Contains openings to permit structures to pass between the 2 cavities.
- Skeletal muscle with unusual central tendon.
- Left and right domes, right more superior due to presence of liver.
- Muscular part attaches peripherally to: Sternum, lower 6 ribs, costal cartilages & L1-L3 vertebral bodies.
- Muscle part supplied by phrenic nerve.
What is supplied by phrenic nerve (C3, 4 & 5 anterior rami)
Muscular part of diaphragm
Why is the right dome of diaphragm higher?
Presence of liver inferiorly.
What does the muscular part of the diaphragm attach peripherally to?
Sternum, lower 6 ribs &costal cartilages & L1-L3 vertebral bodies
Phrenic nerves
Combined anterior rami of cervical spinal nerves C3, 4 & 5.
Where is phrenic nerve found?
- Neck: On anterior surface of scale us anterior muscle.
- Chest (Thorax): Descending over lateral aspects of the heart.
What does the phrenic nerve supply?
Somatic sensory & sympathetic axons to diaphragm & fibrous pericardium & somatic motor axons to the diaphragm.
Inspiration mechanics
- Diaphragm contracts & descends.
- Intercostal muscles contract elevating ribs.
- Chest walls pull the lungs outwards with them (pleura)
Expiration Mechanics
- Diaphragm relaxes & rises.
- Intercostal muscles relax, lowering ribs.
- Elastic tissue of lungs recoils.
Anatomy of Breast
Pectoral fascia, pectoralis Major, pectoralis minor, ribs, intercostal muscles, parietal pleura, subclavian & internal thoracic artery & vein.
Unilateral drainage
From lateral quadrants to axillary nodes
Bilateral drainage
From medial quadrants to parasternal nodes
Superficial fascia
Adipose tissue, insulation
Deep fascia
Fibrous, tough, protection
Muscles of chest wall
Pectoralis major, lattimus dorsi, serratus anterior, deltoids, pectoralis minor.
Cervical parietal pleura
Above rib 1
Costal parietal pleura
From rib 1 to lung base
Diaphragmatic parietal pleura
Spans area where lung & diaphragm meet.
Mediastinal parietal pleura
Spans area where lung & mediastinum meet
Costophrenic angle
Where costal pleura & diaphragmatic pleura meet.
Costodiaphragmatic recess
Inferior part of pleural cavity, located between diaphragmatic and costal parietal pleura.
Where does abnormal fluid in pleural cavity drain?
Into costodiaphragmatic recess
What does abnormal fluid in costodiaphragmatic recess cause?
Blunting of angles & fluid level seen on CXR
Root of the lung
- 1 main bronchus.
- 1 pulmonary artery.
- 2 pulmonary veins.
- Lymphatics, visceral afferent, sympathetic nerves & parasympathetic nerves.
Afferent nerves
Sensory -> CNS
Efferent nerves
CNS -> Muscle
Right Lung: Surface markings
Root of lung, azygous vein, phrenic nerve, superior vena cava, heart, diaphragm, inferior vena cava
Hilum of Lung
Main bronchi, pulmonary arteries, pulmonary lymph nodes (black), pulmonary veins
Left Lung: Surface Markings
Aorta, heart, diaphragm, root of lung, phrenic nerve, common carotid artery.
Auscultation
Anterior: Lung apex (superior to clavicle), Middle lobe (between ribs 4&6).
Posterior: Lung base (Level of T11 vertebrae)
What level is the horizontal fissure of Right Lung?
Follows right rib 4
What level is the oblique fissures?
Level of rib 6 anteriorly rising to T3 vertebral level posteriorly.
Coughing
Stimulation of sensory receptors in:
- Oropharyngeal mucosa.
- Laryngopharyngeal mucosa.
- Laryngeal mucosa.
What sensory receptors are stimulated in sneezing?
CNV or CNIX
What sensory receptors are stimulated in coughing?
CNIX or CNX
Carotid sheaths
Protective tubes of cervical deep fascia.
What does the carotid sheath attach superiorly to?
Bones of the base of the skull.
What does the carotid sheath contain?
Vagus nerve, internal carotid artery, common carotid artery & internal jugular vein
What does the carotid sweat blend inferiorly with?
Fascia of the mediastinum
Affect of stimulation of sensory receptors in LRT respiratory mucosa
- Motor axons travel from tracheal bifurcation along branches of resp tree to supply all mucous glands & all bronchiolar smooth muscles.
- Pulmonary visceral afferent travel from visceral pleura & resp tee to plexus then follow vagus nerve to medulla of brainstem
Where do motor axons, that supply mucous glands & bronchiolar smooth muscle, travel from?
Tracheal bifurcation, along branches of resp tree
Where to pulmonary visceral afferents travel form to reach the medulla of the brain stem?
Visceral pleura & resp tree to plexus and then follow vagus nerve to medulla
What nerve do pulmonary visceral afferents follow to the medulla from plexus?
Vagus
Coughing involves stimulation of sensory receptors in the mucosa of what?
Respiratory tree
What muscles are used in a deep inspiration?
Diaphragm, intercostal muscles & accessory muscles of inspiration
How does the CNS co-ordinate a deep inspiration?
- Diaphragm: Phrenic nerve supplies greater outflow of action potentials of longer duration causes diaphragm to flatten and then descend maximally.
- Intercostal muscles contract forcefully & raise ribs maximally: Intercostal nerves.
Intercostal nerves
Anterior rami of spinal nerves T1-T11
Accessory muscles of forced inspiration
Pectoralis major, pectoralis minor, sternocleidomastoid, scalenus anterior, medius & posterior.
Pectoralis Major
- Attaches between sternum/ribs & humerus.
- Adducts & medically rotates humerus.
- Upper limb position fixed.
- Muscle can pull ribs upwards/outwards.
Pectoralis Minor
- Can pull ribs 305 superiorly towards coracoid process of the scapula.
Clinical sign suggestive of dyspnoea?
Recruitment of accessory muscles.
Sternocleidomastoid
- Attaches between sternum/clavicle & mastoid process of temporal bone.
Scalenus anterior, medius & posterior
Attach between cervices vertebrae & ribs 1 & 2.
What does adduction of the vocal cords cause?
Closure of rima glottidis.
Where do intrinsic muscles attach between?
Cartilages of larynx
What does movement of cartilages in larynx cause?
Movement of vocal cords
Affect of cough reflex on intrinsic muscles of larynx?
Causes intrinsic muscles of larynx to adduct the vocal cords
What nerve supplies the intrinsic muscles of the larynx?
All supplied by (somatic) motor nerve - branches of the vagus nerve (CN X)
What type of muscle is the intrinsic muscles of the larynx?
All skeletal (voluntary) muscles.
Where do the right and left vagus nerves connect with the CNS?
At the medulla (oblongata) of the brainstem
What type of nerve is the vagus nerves?
Both sensory & motor nerve
Function of vagus nerves in neck
- Supply somatic sensory axons to the muscles a lining of the larynx.
- Supply somatic motor axons to the intrinsic muscles of the larynx.
Function of vagus nerves in chest
Supply parasympathetic axons to chest organs
Route of vagus nerves
Medulla of brainstem -> jugular foramen -> descend through neck within carotid sheath -> descent posterior in chest to lung root -> pass through diaphragm on the oesophagus -> divide into many parasympathetic branches on surface of stomach for the foregut & midgut organs.
Accessory muscles of forced expiration
Abdominal wall muscles
How does CNS coordinate deep expiration?
Intercostal nerves stimulate contraction of right & left anterolateral abdominal wall muscles to build up intra-abdominal pressure which pushes the diaphragm superiorly & builds up pressure in the chest/resp tree inferior to the adducted vocal cords
Anterolateral abdominal wall muscles
Right & left rectus abdominis, right & left external oblique, right & left internal oblique, right & left transversus abdominus.
Where does aponeurosis of right & left external oblique blend?
Midline linea alba
What attaches to the right external oblique superiorly?
Superficial aspects of lower ribs
What attaches to the right external oblique inferiorly?
Anterior part of iliac crest & pubic tubercle
Linea semilunaris
Where muscle fibres end & aponeurosis begins
What attaches to right internal oblique superiorly?
Inferior border of lower ribs
What attaches to right internal oblique inferiorly?
Iliac crest & thoracolumbar fascia of lower back.
Where does aponeurosis of right & left internal oblique blend?
Midline linea alba
Where does aponeurosis of right & left transverse abdominus blend?
Linea alba
What attaches to transversus abdominus superiorly?
Deep aspect of lower ribs.
What attaches to transverse abdominus inferiorly?
Iliac crest & thoracolumbar fascia of lower back.
Functions of anterolateral abdominal muscles
- Tonic contractions maintain posture, & support the vertebral column.
- Contractions produce movements of vertebral column.
- Guarding contractions protect abdominal viscera.
- Contractions increase intra-abdominal pressure to assist defecation, micturition & labour.
- Contractions aid forced expiration.
Affect of abduction of vocal cords on rima glottidis
Opens rima glottidis.
How does CNS direct stream of air through oral cavity as a cough rather than nasal cavity as a sneeze?
Soft palate tenses (CN V) & elevates (vagus nerves) to close of entrance into Nasopharynx & direct stream of air.
Complications of dynamic airway compression in asthma
- Expiration difficult.
- Build up of air trapped in alveoli can lead to rupture of Lung & visceral pleura.
How does alveolar air enter the pleural cavity?
Through a breach in the visceral pleura
Small pneumothorax
< 2cm gap between lung and parietal pleura, when a small amount fo air enters the pleural cavity.
Cause of small pneumothorax
- Penetrating injury to parietal pleura.
2. Rupture of visceral pleura.
How does injury to parietal pleura/rupture of visceral pleura cause a small pneumothorax?
Vacuum is lost, elastic lung tissue recoils towards lung root & small pneumothorax results.
Large pneumothorax
> 2cm gap between lung & parietal pleura, when a large amount of air enters the pleural cavity
What causes large pneumothorax?
- Penetrating injury to the parietal pleura.
2. Rupture of visceral pleura.
How does injury to parietal pleura/rupture of visceral pleura cause a large pneumothorax?
Vacuum is lost, elastic lung tissue recoils towards lung root & large pneumothorax results.
Pneumothorax: Auscultation
Reduced ipsilateral breath sounds
Pneumothorax: Percussion
Hyper-resonance
Pneumothorax: Chest expansion
Reduces ipsilateral chest expansion
Pneumothorax: CXR
- Absent lung markings peripherally.
- Lung edge visible (red arrows)
How does a tension pneumothorax occur?
Torn pleura can create a one-way valve that permits air to enter the pleural cavity on each inspiration but prevents air escaping again on expiration => on each inspiration more air enters pleural cavity (Increasing intrapleural pressure with each expiration) => pneumothorax expands => lung collapses towards its root => Eventually build up of air in pleural cavity applies tension to mediastinal structures.
In pneumothorax how does air enter pleural cavity on inspiration but air preventing from escaping on expiraton?
Torn pleura can create a one way valve
How does tension pneumothorax cause mediastinal shift?
Build up of air in pleural cavity applies tension to mediastinal structures => mediastinum shifted
What level is the superior mediastinum?
Level of Sternal angle
Consequences of mediastinal shift
- Tracheal deviation, away from side of unilateral tension pneumothorax, palpable in the jugular notch.
- SVC compression reduces venous return to the heart leading to hypotension.
Management of large pneumothorax
- Needle aspiration.
2. Chest drain.
Safe triangle
- Anterior border of latissimus dorsi.
- Posterior border of pectoralis major.
- Axial line superior to nipple.
Emergency management of tension pneumothorax
Large gauge cannula inserted into pleural cavity via 2nd or 3rd intercostal space in mid-clavicular line on side of tension pneumothorax.
What does cannula pass through in emergency management of tension pneumothorax?
- Skin.
- Superficial/deep fascia.
- 3 layers of intercostal muscles.
- Parietal pleura.