Pulmonary Arterial Hypertension-1 Flashcards

1
Q

Who it happens to

A

Women
20-40
Rare

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2
Q

Problem with pulmonary arterial hypertension

A

Blood vessel construction and resistance in the lungs

Hypoxia
Right sides heart failure
Death in two years

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3
Q

Genetic mutation

A

50% of patients

BMPR2 gene

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4
Q

Severity classification of PAH

A

Class 1- least: no limitation of physical activity

Class 4- worst: complete limitations

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5
Q

Diagnosis

A

Abnormal ventilation
Right sided heart Cath
Pulmonary function tests
CT

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6
Q

Endothelin-receptor agonist

A
-ntan
Tablet
Glass of water
With or without food
More contraception 
No ETOH
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7
Q

Prostacyclin agents

A

Best
Continuous infusion
Subcut

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8
Q

Also use this drug

A

Sildenafil
Warfarin
Bosentan

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9
Q

PAH outcome

A

Use O2
Digoxin, diuretics
Lung
Lung and heart transplant (cor pulmone)

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