Myasthenia Gravis Flashcards
Definition
Acquired autoimmune disease characterized by muscle weakness
Two types
Ocular
Generalized
Worsen with
Exercise and improve with rest
Death from
Respiratory failure
Fatigue and weakness of
Cranial nerves
Skeletal muscles
Respiratory muscles
Caused by
Distorted acetylcholine receptors in the muscle end plate membranes
Nerve impulses do not generate muscle contraction
Thymoma
Encapsulated brain tumor
Causes abnormal growth of thymus gland
Motor manifestations
Muscle weakness that improves with rest Poor posture Ocular palsied Ptosis Diplopia Respiratory compromise Bowel and bladder Fatigue
Sensory manifestations
Muscle achiness
Paresthesias
Decreased sense of smell and taste
Onset
Insidious
Bulbar involvement
Affected
Facial expression
Chewing
Speech
The patients face
Snarl instead of smile Hanging jaw (they might prop it up)
Periods of remission
And exacerbation
Rapid development may be caused by
Infection
Pregnancy
Anesthesia
Difficulty with
Climbing stairs
Lifting heavy objects
Raising arms overhead