Pulmonary Flashcards
Acute bronchitis organisms
most likely viral
adenovirus
coronavirus
RSV
Acute bronchitis treatment
symptomatic
Pertussis organism
Bortadella pertussis (G-)
Pertussis stages
catarrhal
paroxysmal
convalescent
Most infectious stage of pertussis
catarrhal
Pertussis labs
nasopharyngeal swab
Pertussis treatment
1st line: Macrolides
-Azithromycin
Tdap booster
Prophylaxis for close contacts
CAP organisms
- Streptococcus pneumoniae
- Haemophilus influenza
Gold standard for CAP diagnosis
CXR
CAP lab results
- leukocytosis
- bandemia
CAP treatment for low risk patients
- amoxicillin
- doxycycline
- macrolide
CAP treatment for high risk patients, used abx within last 3 months
-Augmentin or cefpodoxime or cefuroxime AND
Macrolide or doxycycline
-Levaquin
CAP high risk patients
- > 65
- immunocompromised
- multiple comorbidities
- recent antibiotic use
- day care attendance, LTC facilities
PPSV23 only
increased risk patients -asthma COPD smoking CVD DM liver disease
pneumococcal schedule for very high risk patients
PCV13 now
PPSV23 in 8 weeks
PPSV23 in 5 years (booster)
pneumoccoccal for >65 and healthy
PPSV23 only
> 65 and immunocompromised for pneumococcal
PCV13 now
PPSV23 in 1 year
Pneumococcal dosing for <2 years old
2 months
4 months
6 months
12-15 months
Children >2 who have not been pneumococcal vaccinated
1 dose PCV13
Atypical PNA organisms
- mycoplasma pneumoniae
- chlamydia pneumoniae
- Legionella pneumoniae
Atypical PNA treatment
-macrolide
azithromycin
clarithryomycin
erythromycin
Phlegm color in bacterial PNA
rust colored
COPD components
- emphysema
- chronic bronchitis
- possible asthma
COPD with emphysema presentation
- barrel chest
- increased AP diameter
- accessory muscle use
- pursed lip breathing
- weight loss
COPD with chronic bronchitis presentation
- chronic cough
- sputum production
- coarse crackles
Inhaled anticholinergic mechanism
prevent bronchoconstriction
Beta agonist mechanism
produce bronchodilation
What to add to first line treatment for CODP
- SAMA, LABA
- SABA
Examples of SAMA
-ipratropium (Atrovent)
Examples of LAMA
-tiotropium (Spiriva)
Example of LABA
- salmeterol
- indacaterol
- olodaterol
SAMA SABA combo
Ipratropium/albuterol (Combivent)
alpha-1-trypsin deficiency
- rare
- severe lung damage at early ages
- early onset COPD
When to avoid SAMA/LAMA
narrow-angle glaucoma
BPH
bladder neck obstruction
General treatment of COPD
- smoking cessation
- annual flu
- pulmonary rehab therapy
- treat lung infections aggressively
Consider which organism with PNA in COPD
Haemophilus influenzae
need gram - coverage antibiotics
Lung cancer screening recommendations
- annual low-dose CT for current smokers 55-80 with 30 pack-year history
- patients who have quit smoking within the last 15 years
What level of prevention is lung cancer screening
secondary
Inhaled ICS examples
- Fluticasone (Flovent)
- Triamcinolone (Azmacort)
- Beclamethasone (Qvar)
- Budesonide (Pulmicort)
Teaching needed for inhaled ICS
- oral thrush, wash out mouth after use
- HPA axis suppression
LABA patient education
-warm of increased risk of asthma deaths
Leukotriene inhibitor examples
- Montelukast (Singulair)
- Zileuton (Zyflo)
Montelukast monitoring
-nueropsychological effects
Zileuton monotiroing
LFTs
Mast cell stabilizer examples
- Cromolyn
- Nedocromil
Methylxanthine examples
-Theophylline
Immunomodulators
Omalizumab (anti-IgE)
Mild intermittent asthma
- FEV1/PEF >80%
- symptoms <2x/week
- SABA PRN
Mild persistent asthma
- FEV1/PEF >80%
- Symptoms >2x/week
- SABA PRN + low dose ICS
- alt: Cromolyn, montelukast, theophylline, nedocromil
Moderate persistent asthma
- FEV1 or PEF 60-80%
- daily symptoms
- SABA PRN + low dose ICS with salmeterol (Advair) or medium-dose ICS
- alt: low dose ICS plus Singulair, theophylline, or zileuton
Severe persistent asthma
- FEV1/PEF <60%
- symptoms most of the day
- high dose ICS +LABA plus daily oral steroid
- SABA
Exercise induced asthma
- premedicate 10-15 minutes before activity
- effect lasts up to 4 hours
Asthma exacerbation treatment
- albuterol neb treatment
- may repeat every 20 minutes up to 3 doses
- if unable to use give epi IM
Peak expiratory flow rate
measures effectiveness of treatment, worsening symptoms, and exacerbations
-blow hard three times onto spirometer, highest value is recorded as best
Mnemonic for PEF
HAG
- height
- age
- gender
Spirometer green zone
- 80-100% expected
- maintain or reduce medications
Spirometer yellow zone
- 50-80%
- maintain or increase if having exacerbation
Spirometer red zone
<50%
- call 911 if after treatment
- if in respiratory distress, give IM epi and call 911
Chronic use of high-dose inhaled steroids
- osteoporosis
- mild growth retardation
- glaucoma
- cataracts
- immune suppression
- HPA suppression
What to do if you suspect allergic asthma
- check serum IgG allergy panels
- refer to allergist
Menopausal women on me to high dose ICS long term
-consider calcium and vitamin D supplement
TB organism
-mycobacterium tuberculosis
most contagious TB
pulmonary
pleural
larygneal
Is latent TB infectious
no
Miliary TB
- infects multiple organ systems
- younger children <5
- elderly
- milia seed pattern on xray
First line drugs for TB
-isoniazid and rifampicin
Direct observed treatment for TB
- for non–compliant patients
- nurse needs to physically see them take their medication
What to do with positive PPD
- assess for s/sx
- order CXR
Latent TB treatment
- HIV (-): INH for 9 months
- HIV (+): INH for 12 months
- monitor LFTS
Who to treat latent TB
- recommended for <35yo
- less risk of liver damage
Positive TB test <5 mm
- HIV (+)
- recent contact
- CXR with fibrotic changes with previous TB
- any child (<5) with close TB contact
- IC
Positive TB for >10
- recent immigrant (within last 5 years)
- child <4 or adolescent exposed
- IVDU
- Health care worker
- homeless
- employee in high risk setting
Positive TB >15
anyone with no known risk for TB
Preferred test for BCG vaccination
- IGRA
- available within 24 hours
Purpose of 2 step TB test
- booster phenomenon
- person will have false negative to first test if not tested for many years
- repeat in 1-3 weeks, will be positive if patient has TB
How many drugs should TB be treated with
at least 2 or 3
Category A (GOLD 1-2) treatment
-SABA PRN
OR
-SABA/SAMA
Category B (GOLD 1-2) treatment
- LABA or LAMA
- SABA PRN
Category C (GOLD 3-4) treatment
- LAMA
- if poor control use LABA and LAMA
Category D (GOLD 3-4) treatment
- high risk
- refer to pulmonologist
Most common cause of COPD exacerbations
bacterial or viral cause
COPD exacerbation antimicrobial treatment options
- Concern for Haemophilus influenzae infection
- Bactrim DS, doxycyline, or Ceftin
- severe: Augmentin or respiratory quinolones
- Medrol dose pack
1 cause of CAP in cystic fibrosis patients
Psudomonas aeruginosa
COPD lung changes
- reduction in FEV1
- increase RV
- increase TLC