Evidence based medicine Flashcards
Evidence base medicine definition
-conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients
Lowest ranking of research evidence
- expert or specialty group onions
- editorials
Middle ranking of research evidence
- RCT
- experiment
- cohort study
- case reports/series
Highest level of research evidence
- meta-analysis
- systematic review
Meta-analysis
-statistical method that combines data from multiple studies resulting in higher statistical power and a single conclusion
Gold standard for gathering research and evidence for EBM
meta-analysis
Systematic review
- type of literature review that identifies, selects, and analyzes multiple research articles
- specific methodlogy
- studies ranked from Grade A (best evidence) to D (poor evidence)
What happens when systematic review is completed
-acceptable studies are pooled together and statistical testing of data (meta-analysis) is performed
Randomized Controlled Trial
- assigned either control or treatment group
- some use double-blind design
- experimental studies
What is an experimental study
-random subject selection
one placebo or control group
one or more intervention groups
Cohort study is a type of what study
prospective study
Case report
-detailed report of one patient with disease, includes demographics, sign/sx, diagnosis, response to treatment, etc.
Case series
-series of case reports that involves a series of individuals who are given similar treatment
Opinions and editorials
- biased and not based on solid evidence
- weakest form of evidence
Gold standard database and resource for EBM
Cochrane review