Pulmonary Flashcards
Methacholine/Bronchial Challenge Test
FEV1 falls by 20%
High NPV
Bronchodilator Challenge in Asthma
increase of 12% and at least 200 mL.
Allergic bronchopulmonary aspergillosis
severe asthma
elevated IgE
positive skin tests for Aspergillus
α1-antitrypsin testing in COPD
when diagnosed under 45 years of age
Bronchiectasis Diagnosis
airway diameter greater than that of its accompanying vessel, and lack of distal airway tapering.
Break down of ILD/DPLD
- smoking related
- steroid responsive
- connective tissue related
- exposure related
Smoking Related ILD/DPLD
1) DIP: Desquamative Interstitial Pneumonia
2) RBLD: Respitoray Bronchiolitis ILD
3) PLCH: Pulmonary Langershans Cell Histiocytosis
4) Idiopathic pulmonary fibrosis
Connective Tissue ILD/DPLD
RA and systemic sclerosis are most common
Steroid Responsive ILD
sarcoidosis
organizing PNA
eosinophilia PNA
hypersensitivity PNA
Organizing Pneumonia
peripheral sparing on CT
often follows acute infection, radiation exposure, or autoimmune disease
called cryptogenic if no cause is found
Treatment of Sarcoidosis Lung Disease
depends on the stage, earlier stages can be managed with observation and may spontaneously resolve
prednisone for more severe stages
Time Frame for Asbestos Related Disease
15-35 years
Risk Factors for Asbestos Related Disease
mine works, construction, naval shipyards, automotive
Asbestos Lung Disease Imaging Findings
Pleural Plaques or calcifications
Risk Factors for Silicosis
concrete, tile, and masonry
What to consider with worsening silicosis
TB
Lights Criteria
Pleural to serum protein >.5
Pleural to serum LDH >.6
LDH>2/3 ULN
Pleural Fluid Cholesterol
> 55 consistent with exudative
pH and Pleural fluid
less than 7.2 = complicated pleural effusion
Pleural Fluid amylase evaluates for
esophageal rupture, pancreatitis
Pleural Fluid triglycerides evaluates for
chylothorax
Causes of Chylothorax
Malignancy (lymphoma)
TB
Surgery/Disruption of Thoracic Duct
How to Diagnose TB in Pleural Effusion
Adenosine deaminase (ADA)
Definition of Parapneumonic Effusion
effusion associated with a pneumonia