Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PGY-4 Board Prep > Oncology > Flashcards

Oncology Flashcards

1
Q

Most common posterior fossa mass

A

medulloblastoma (typically age 5-7)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Ewing Sarcoma

A

onion-skin appearance/laminated periosteal reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Acanthosis Nigricans association with cancer

A

gastric cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Gastric Cancer Associations

A
  • acanthosis nigricans
  • Trousseau syndrome
  • Leser-Trelat (diffuse SKs)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Treatment for Metastatic Prostate Disease

A

mainstay if ADT including orchiectomy, GnRH agonist or GnRH antagonist
also docetaxel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Gleascon Scores that are typically low risk

A

less than or equal to 6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Types of Non Small Cell Lung Cancer

A

Adenocarcinoma
Squamous cell carcinoma
large cell carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Adenocarcinoma Lung Cancer

A

ususally peripheral located

non-smokers as well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Squamous Cell Carcinoma / Lung Cancer

A

Usually central airway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Large Cell Carcinoma / Lung Cancer

A

usually with necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

TNM staging

A

T - primary
N - nodes
M - metastasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Canditates for Breast Cancer Chemoprophylaxis

A
  • lobular carcinoma in situ (LCIS)

- atypical hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Breast Cancer Screening in BRCA1/2 patients

A

MRI age 25
mammogram age 30
yearly MRI + mammogram

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Breast Cancer - SERMs

A

Tamoxifen + Raloxifene

pre or postmenopausal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Breast Cancer - Aromatase Inhibitors

A

Anastrozole + Exemestane

postmenopausal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Breast Cancer - DCIS treatment

A

lumpectomy, can be followed by masectomy + radiation

ER+: tamoxifen or AIs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Breast Cancer - When is Lumpectomy + RT preferred

A

tumors less than 5 cm +w/o high risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Breast Cancer - Duration of SERMS + AIs

A

at least 5 years, preferably 10

19
Q

Transtuzamb AE

A

cardiomyopathy, fever, chills

20
Q

Breast Cancer Triple Negative Adjuvant Chemo

A

doxorubicin + cyclophos + taxane

21
Q

BRCA 1/2 Cancers: Agent if multiple failed regiments

A

poly (ADP-ribose) polymerase (PARP) inhibitor: olapurib

22
Q

Metastatic Breast Cancer/Reoccurrence First Line Agents

A

Fulvestrant (inhibit estrogen receptor function)

CDk4/6 Inhibitor: Palbociclib

23
Q

Ovarian Cancer Risk Factors

A

age, nulliparity
PCOS, endometriosis
IUD, cigarette smoking
BRCA 1/2, Lynch Syndrome (HNPCC)

24
Q

Ovarian Cancer Treatment

A

surgery (sometimes alone)

platinum-taxane chemo (IP & IV)

25
Q

Drug for Metastatic Cervical Cancer

A

Bevacizumab (anti-VEGF)

26
Q

Cervical Cancer Treatment

A

surgery
+/- chemo (platinum based)
+/- radiation

27
Q

Rectal Cancer Treatment

A

RADIATION + chemo +/- surgery

28
Q

Colorectal Cancer Treatment - Stage I & II

A

Surgery

29
Q

Colorectal Cancer Treatment - Stage III

A

LN involvement

surg + chemo (FOLFOX or CAPOX)

30
Q

Colorectal Cancer Treatment - Stage IV

A

LNs + organs
Chemo (FOLFOX or CAPOX)
bevacizumab/VEGF

31
Q

Colorectal Cancer - Associated Mutations

A

KRAS, NRAS, BRAF

32
Q

Adjuvant Chemotherapy for Pancreatic Cancer

A

gemcitabine + capecitabine

33
Q

Gastrointestinal Stromal Tumors

A
  • types of sarcomas
  • associated with KIT gene, DOG-1
  • Treat with imatinib
34
Q

NSCLC Treatment

A

early stage: surgical resection +/- chemo (cisplatin)

advanced - chemo + surg or chemo + RT

35
Q

NSCLC Metastatic Disease Treatment and Targeted Therapy

A

EGFR (ALK or ROS), crizotinib

PD-LI such as pembrolizumab

36
Q

Small Cell Lung Cancer required imaging for diagnosis/staging

A

whole body bone scintigraphy + MRI of the brain (60% with mets to brain at diagnosis)

37
Q

Small Cell Lung Cancer Treatment

A

cisplatin + etopiside + radiation

prophylatic cranial irriadiation

38
Q

Head and Neck Cancer Treatment

A

surgery
sometimes radiation for larynx
metastatic = chemo (cisplatin)

39
Q

Seminoma treatment

A

Radiation + Surgery +/- Chemo (cisplatin)

40
Q

Nonseminoma treatment

A

Surgery + Chemo (cisplatin) + RPLND (retroperitoneal LN dissection)

41
Q

Renal Cell Carcinoma Neoparaplastic Syndromes

A

hypercalcemia
anemia or erythrocytosis
AA amyloidosis
polymyalgia rheumatic

42
Q

Stauffer Syndrome

A

hepatic dysfunction w/o liver mets in RCC

43
Q

RCC Treatment

A

radical/partical nephrectomy
Sunitinib
PD-L1 nivolumab
VEGF inhibitiors levatinib

44
Q

Oligometastatic colon cancer

A

less than three lesions in liver –> resect

PGY-4 Board Prep (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions