MKSAP Pearls

Question 1

Chronic/Active Hepatitis B during Pregnancy

Answer 1

tenofovir

Question 2

Carotid Duplex Ultrasound vs CT angiography for diagnostic purposes

Answer 2

U/S: carotid stenosis

angiography: PAD, atherosclerotic disease

Question 3

Inhaled Steroid for Asthma During Pregnancy

Answer 3

Budesonide

Question 4

Primary Ovarian Insufficiency in Adults

Answer 4

less than age 40, secondary amenorrhea, two FSH in post-menopausal range

Question 5

Diverticulitis and Colonoscopy

Answer 5

perform 4-8 weeks after resolution of episode to evaluate for colon cancer

Question 6

Aldrenodate for Osteoporosis and Discontinuation

Answer 6

can consider after 5 years if stable

Question 7

Differential for Celiac Disease

Answer 7

medication induced enteropathy, esp olmesartan

Question 8

low risk MGUS, IgG of

Answer 8

less than 1.5

Question 9

Intracranial HYPOtension

Answer 9

orthostatic headache
due to CSF leakage
Rx w/ epidural blood patch

Question 10

Anemia of Chronic Disease - classic labs that are low

Answer 10

low iron + low TIBC

Question 11

erythrocyte cast appearance

Answer 11

tubular structure

small granular spherocytes within them

Question 12

Immune Mediated Necrotizing Myopathy

Answer 12

due to statins, can continue to worsen despite d/c

Rx with steroids

Question 13

Where does pemphigus vulgaris start?

Answer 13

Mouth/oral membranes

Question 14

MIC & Susceptibility

Answer 14

<2 susceptible

4-8 are intermediate

Question 15

Treatment of Early Stage Laryngeal Cancer

Answer 15

radiation

Question 16

Intraductal Papillary Mucinous Neoplasms

Answer 16

dilation of pancreatic duct w/o clear sign of lesion

mucin secreted from ampulla of vater

Question 17

Aspirin and Colonoscopies

Answer 17

No need for discontinuation

if polypectomy, can consider holding if primary prevention is indication

Question 18

Thrombocytosis/Leukocytosis/Etc - what to consider first

Answer 18

EPO, should be normal/low

if high think paraneoplastic i.e. RCC

Question 19

Associations with ITP

Answer 19

HIV

Question 20

When can you not use TSH as a marker of thyroid function

Answer 20

in secondary hypothyroidism, ex pituitary apoplexy etc where the gland can’t make hormones

Question 21

gastric antral vascular ectasia (GAVE)

Answer 21

watermelon striped appearance

associated with systemic sclerosis

Question 22

Cameron lesions

Answer 22

erosions found on the crest of gastric folds within a large hiatal hernia and are thought to be caused by mechanical trauma as the hiatal hernia slides up and down

Question 23

Meltzer Triad

Answer 23

consisting of asthenia, arthralgia, and palpable purpura—which is the classic presentation of type II mixed cryoglobulinemia

Question 24

Chemo for Lynch Syndrome/mismatch repair genes

Answer 24

immune checkpoint inhibitors, such as pembrolizumab or nivolumab

Question 25

anti-U1-ribonucleoprotein (RNP) antibodies.

Answer 25

mixed connective tissue disease

mortality is PAH

Question 26

Dexamethesone Suppression Test & Cushings

Answer 26

> 5 considered positive

Question 27

PPI and Renal Disease

Answer 27

chronic TIN

usually presents in 6-9 months

Question 28

Chronic Fatigue in Multiple Sclerosis Rx

Answer 28

Modafinil

Question 29

Pyoderma Gangreosum Treatment

Answer 29

prednisone

Question 30

medication for impaired mobility in MS

Answer 30

dalfampridine