GI Flashcards
Hepatitis B: Immunized
Anti-HBs
Hepatitis B: Acute Infection
+HBsAg
+ Anti-HBc IgM
+ HBeAg
Hepatitis B: Resolved Infection
Anti-HBs
+ Anti-HBc IgG
+/- Anti-HBe
Hepatitis B Treatment
Entecavir or tenofovir
Hepatitis B Phases
Immune tolerant
immune active
immune control/carrier
Reactivation
Hepatitis C Treatment Cure (lab)
no HCV RNA in blood 12 weeks after completion of treatment
Autoimmune Hepatitis Antibodies
Type 1 - Antismooth muscle, ANA, elevated IgG
Type 2 - Anti-LKM and ALC
Alpha 1 AntiTrpysin Genotype
ZZ = severe disease
MZ or SZ = disease only in setting of other liver disease
Initial Testing for Hereditary Hemochromatosis
Elevated transferrin saturation
Wilson Disease Screening
low ceruloplasmin, high urinary copper
Wilson Disease, typical age for presentation
5-40
Treatment of Wilson Disease
Trientine > pencillamine
Zinc supplementation
Primary Biliary Cholangitis Labs
elevated ALP
+ antimitochondrial Ab
Primary Biliary Cholangitis Screening
yearly TSH for AI thyroid disease
Diagnosis of Primary Sclerosing Cholangitis
MRCP w/ colonoscopy at diagnosis
beading seen on ERCP