GI Flashcards

1
Q

Hepatitis B: Immunized

A

Anti-HBs

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2
Q

Hepatitis B: Acute Infection

A

+HBsAg
+ Anti-HBc IgM
+ HBeAg

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3
Q

Hepatitis B: Resolved Infection

A

Anti-HBs
+ Anti-HBc IgG
+/- Anti-HBe

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4
Q

Hepatitis B Treatment

A

Entecavir or tenofovir

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5
Q

Hepatitis B Phases

A

Immune tolerant
immune active
immune control/carrier
Reactivation

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6
Q

Hepatitis C Treatment Cure (lab)

A

no HCV RNA in blood 12 weeks after completion of treatment

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7
Q

Autoimmune Hepatitis Antibodies

A

Type 1 - Antismooth muscle, ANA, elevated IgG

Type 2 - Anti-LKM and ALC

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8
Q

Alpha 1 AntiTrpysin Genotype

A

ZZ = severe disease

MZ or SZ = disease only in setting of other liver disease

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9
Q

Initial Testing for Hereditary Hemochromatosis

A

Elevated transferrin saturation

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10
Q

Wilson Disease Screening

A

low ceruloplasmin, high urinary copper

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11
Q

Wilson Disease, typical age for presentation

A

5-40

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12
Q

Treatment of Wilson Disease

A

Trientine > pencillamine

Zinc supplementation

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13
Q

Primary Biliary Cholangitis Labs

A

elevated ALP

+ antimitochondrial Ab

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14
Q

Primary Biliary Cholangitis Screening

A

yearly TSH for AI thyroid disease

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15
Q

Diagnosis of Primary Sclerosing Cholangitis

A

MRCP w/ colonoscopy at diagnosis

beading seen on ERCP

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16
Q

Diuretic Ratio for Cirrhosis/Ascites

A

Furosemide 20 : Spironolactone 50

17
Q

Ascites Studies consistent with Cirrhosis

A

SAAG >1.1

Low ascetic protein (<2.5)

18
Q

SBP Diagnosis

A

PMN >250

19
Q

When to consider albumin co-administration for SBP

A

Renal Dysfunction, Cr >1, BUN >30

TB >4

20
Q

Gallbladder polyps - when to intervene

A

size >1cm, symptoms, increasing in size

21
Q

Cholangitis - Tetrad and Pentad

A

Charcot: Fever, jaundice RUQ Pain
Reynolds: hypotension, AMS

22
Q

Hep A pre exposure prophylaxis

A

most - Hep A Vaccine
consider IG if immunocompromised OR endemic region in 2 weeks + unvaccinated
liver disease + traveling + unvaccinated: vaccine + IG w/in 2 weeks

23
Q

Hep B Extrahepatic manifestations

A

arthritis
polyarteritis nodose
MN
cyroglobulienmias

24
Q

Hepatitis C Extrahepatic manifestations

A

cryoglobulienic vasculitis, MPGN, porphyea cutanea tardia

25
Q

alcoholic hepatitis DF score for treatment

A

32! –> prednisolone

avoid if active infection, GI bleed, pancreatitis