pulmonary Flashcards
increase on A-a gradient causes
CORRECT WITH O2(V/Q mismatch) -airway disease(asthma,COPD) -interstitial lung disease -alveolar disease(Atelectasis,pneumonia,pulmonary edema) -pulmonary vascualr disease DONNOT CORRECT WITH O2 -right-left shunt
ARDS Dx
- PaO2/FiO2 ratio below 300
- acute onset respiratory distress
- BILATERAL pulmonary infiltrates on CXR
- respiratory failure not completely explainend by heart failure
goal oxygenation on ARDS
PaO2>55mmHg or SaO2>88%
tidal volumes mechanical ventilation onARDS
4-6cc/Kg
pulmonary hypertention
> 25mmHG
Malignant lung nodule
New or enlarging lesions >2cm irregular calcifications or absent age>45 smoker irregular margins
samters triad
asthma
aspirine intolerance
nasal polyps
Obtructive pulmonary Disease
FEV/FVC less than 80%
mild persistent asthma and tx
> 2 weekly NOT DAYLY
2 nights 7Month
low dose steroid
PRN shorts acting beta agonist
Moderate persistent asthma dn tx
DAYLY >1 night/week med dose corticosteroid Long actint B agonist PRN short acting
severe persistent
coninual episodes
high dose steroid, oral steroir
long acting B agonist
PRN short acting
improves COPD survival
- smoking cessation and O2
- influenza and pneumococcal vaccination
O2 inditacion for COPD
hypoxemia
right heart failure
polycythemia
medications contribute to interstitial lung disease
AMIODARONE(foamy macrophages) busulfan nitrofurantoin blomycin radiation long term O2 concentration
antifibrotic agent for interstitial lung disease
pirfenidone
nintedanib
Löfgren syndrome
sarcoidosis type:
bilateral hilar adenopathy
erythema nodosum
arthritis
silicosis related infection
TB
pneumonia types
CAD(S-pneumo)
HAP(gram-negative bacilli)
VAP
lung abscess treatmetn
clinda or penicillin
empyema lab finds
- LDH above 60% of serum level.
- Protein above 50% of serum level.
- White cell count above 1000
- Ph
best initial test in acute exacerbation os asthma
peak expiratory flow(its decreased)
when to intubate a asthma patient
respiratori acidosis( increased PCO2)
patient with obstrutive patern
increased DLCO=
low DLCO=
- increased DLCO=asthma
- low DLCO=emphysema
best initial test for chronic COPD
chest x ray
most accurate test for COPD
PFT
indication for O2 in COPD
- PO2 less o equal to 55mmHg
- Saturation less o equal 88%
- 60mmhg and 90 % when there is HTN,high HCT or cardiomyopathy
single most common cause of bronchiectasis
cystic fibrosis
best initial step for bronchiectasy
chest x-ray
most accurate:high resolution CT
antibiotics for COPD,bronchiectasy and cystic fibrosis
macrolides, cefalosporins,amoxi/clav,quinolones)
atypical pnuemonia(non visible on gram stain and not culturable on standard blood agar)
- Mycoplasma
- Chlamydophila
- Legionella
- Coxiella
- viruses
CURB 65
-confusion
-BUN more than 20
-Respiratori distress
-BP low
-age65
CURB MORE THAN 2= HOSPITALIZATION
CURB MORE THAN4= ICU
treatment of Hospital-acquired pneumonia
antipseudomonal B lactam
ventilator associated pneumonia treatmetn
combine 3 drugs
- antipseudomonal b lactam
- second antipseudomonal
- MRSA(vanco or linezolid)
most accurate test for PCP
broncheoalveolar lavage
PCP treatmen in TMP allergi
2 LINE:clida + primaquine
3 LINE: pentaminidine
PCP profilaxis
- TMP/SMX
- if allergic give ATOVAQUONE OR DAPSONE
single most accurate test for pulmonary TB
pleural biopsy
PPD for health workers
yearly and the cut point its 10mm
dysnea, loud p2 , fine ryales , and clubbing fingers
- pulmonary fibrosis
- idiopathic
- radiation
- drugs:amiodarone,bleomycin,nitrofurantoin,busulfan,
restrictive patern FPT and decrease DLCO
pulmonary fibrosis
firts initial test for pulmonar embolous
WHEN THE HISTORY ITS CLEAR GIVE HEPARIN FIRTS
- chest X ray(hampton pump, and westermark sign)
- EKG(right axis deviation, RV hypertrophy and RBBB)
- ABG(respiratory alkalosis)
criteria for exudative effusion
- pleural/serum protein more than 0.5
- pleural/serum LDH more than 0.6
best prognosis indicator of COPD
FEV
anti TB medicantion contraindicated in pregnancy
Pyrazinamide
abnormal calcificaiton in solitary pulmonary nodude
-stippled,spiculated,eccentric
rapid shallow breathing index(respiratory rate/tidal volume)=
-under 100
patient its ready to be extubated