Oncology/preventive medicine Flashcards

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1
Q

tamoxifen toxicitiy

A

endometrial cancer

clots

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2
Q

aromatase inhibitos tox

A

osteoporosis

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3
Q

traztuzumab

A

decreases risk and recurrent disease

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4
Q

adjuvant chemotherapy indication

A

1-.lesions larger than 1 cm

2-.positice axillary lymph nodes are found

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5
Q

lower mortality in breast cancer

A
  • mammography
  • ER/PR testing,then tamoxifen/raloxifen
  • aromatase inhibitor
  • adjunvant chemoterapy
  • lympectomy and radiation
  • modified radical mastectomy
  • trastuzumab
  • prophylaxis with tamoxifen
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6
Q

lung cancer screening

A

low dose chest CT in a patient with 30 pack-years smoking history YEARLY from 55-80

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7
Q

HPV vaccine indication

A

every womenbetween ages 11-26

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8
Q

pap smear infiaction

A

after 21 every 3 years, or every 5 if HPV DNA testing its made. STOP at 65

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9
Q

ASCUSn + … next step

A

do a HPV DNA test,

-if positive colposcopy.

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10
Q

brest cancer screening indication

A

startin al 4o every 2 year, stop at 75

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11
Q

colonoscopy screening

A

every 10 years after 50 years

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12
Q

shingles vaccine indication

A

everyone over 60

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13
Q

Td indication

A

every 10 years

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14
Q

osteoporsosis screening indication

A

women>65 DEXA

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15
Q

AAA indication

A

all men ever smoking at 65

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16
Q

lipid screening indication

A

men over 35

women over 45

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17
Q

screening for diabetes

A

any patient with hypertension or hyperlipidemia

GENERAL POPULATION IS NO CLEAR

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18
Q

patient over 50

A

use inactivated (DEAD) flu vaccine

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19
Q

hepatitis B vaccine indication

A
  • end stage renla disease( dialysis)
  • healthcare workers
  • diabetes
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20
Q

hepatitis A vaccine indication

A

travelers to coundtries of high endemicity

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21
Q

DEXA scan indication

A

at the age of 65

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22
Q

most common finding lipid profile in methabolic syndrome

A

increase TGC and low HDL

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23
Q

Live vaccines

A
  • MMR
  • zoster
  • varicella
  • live influenza
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24
Q

Malarie prophylaxis for chloroquine-sensitive areas(CENTRAL AMERICA)

  • caribean
  • mexico
  • costarica
  • argetina
  • el salvador
  • paraguay
A
  • chloroquine
  • atovaquone/proguanil(co traindicated in Renal clearance below 30)
  • doxycycline
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25
Q

malarie prophylaxis for chloroquine-resistent areas

A
  • mefloquine

- doxycycline

26
Q

screening for all sexually active women under 25

A
  • PCR for N.gonorrhea and chlamydia

- HIV

27
Q

what to do with a colon polyps?

A

rmeove any polyp larger than 1cm

28
Q

most sensitive modality for ovarian cancer

A

CA125 conviened with a transvaginal ultrasound

29
Q

raloxifeno

A

prevention and treament of osteporosis

30
Q

asthma patients vaccination

A

-inactivated influenza and pneumocco vaccine

31
Q

patients who should recive the inactivated form of influenza insted of the activated

A
  • inmunocompromised
  • cardiovascular, pulmanary,metabollic disease
  • guillina barre
  • pregnant
32
Q

barret esophagous followin after endoscopy finding:

  • WITHOUT dysplasia:
  • LOW dysplasia:
  • HIGH dysplasia:
A
  • WITHOUT dysplasia: endoscopy every 3 years
  • LOW dysplasia: every 6 to 12 m
  • HIGH dysplasia:every 3 month
33
Q

smoking sesation aid

A

nicotine patch and gums as needed

34
Q

if you dont know the inmunization status what to choose:

Td or TdaP?

A

if you dont know give TdaP and inmunoglobulin

35
Q

tetanus vaccination

A
  • CONTAMINATED with dirt,feces,soil or salive(like a bite), requires a tetanus vaccination if the last one was more than 5 years.
  • clean wound 10 years
36
Q

when to screen HNPCC(2 generations, 1 premature)

A

-Colonoscopy at 25 years(YEARLY)

37
Q

FAP when to screen?

A

-SIGMOIDOSCOPY at 12 y

38
Q

when to screen with previous adenomatous poly

A

-COLONOSCOPY every 3-5 Y

39
Q

previos colon cancer history when to screen

A

-COLONOSCOPY 1 year,then at 3years, and every 5 years.

40
Q

Heb B indication

3 dosis

A
  • Birth
  • 2m
  • 6m
41
Q

Rotavirus(2 dosis)

A
  • 2m

- 4m

42
Q

DTaP(5 doses)

A
  • 2m
  • 4m
  • 6m
  • 15m
  • 6y
43
Q

Hib(4 doses)

A
  • 2m
  • 4m
  • 1y
  • 15m
44
Q

PVC13(4 doses)

A

-2m
-4m
-6m
1y

45
Q

polio (SALK) 4 doses

A
  • 2m
  • 4m
  • 6m
  • 6y
46
Q

MMR(2 doses)

A
  • 1y

- 6y

47
Q

VAR

A
  • 1y

- 6y

48
Q

hepA

A

-1y

49
Q

meningococcal

A

-11y

50
Q

vaccine at birth

A

HepB

51
Q

vaccines at 2 months(6 vaccines)

A
  • HepB
  • rotavirus
  • DTaP
  • Hib
  • PVC13
  • polio (SALK)
52
Q

vaccines at 4 months(5 doses)

A
  • RV
  • DTaP
  • Hib
  • PVC13
  • SALK
53
Q

vaccines at 6 months(3 dosis)

A
  • HepB
  • DTaP
  • PVC13
  • SALK
54
Q

live vaccines

A
  • MMR
  • sabin(polio)
  • yellow fever
  • influenza(nasal)
55
Q

killed vaccines

A
  • cholera
  • HAV
  • SALK
  • rabies
  • influenza(IM)
56
Q

what happens if you lower the cut off point

A

-INCREASE IN SENSITIVITY

increase in True positive

57
Q

what happens if you increase the cut off point

A

-INCREASE IN SPECIFICITY

58
Q

type 1 errer(alphs)

A

false postive(null hypothesis is incorrectly rejected)

59
Q

type II error(betha)

A

false negative (null hypothesis is not rejected when it is in fact false)

60
Q

Relative rist over 1

A

disease is more likely to occur in the exposed group

61
Q

reative risk under 1

A

disease is less likely to occur in the exposed group (PROTECTIVE)