Pulm circulation Flashcards
Pulmonary circulation:
characteristics
Low resistance,
high compliance
PO2 and PCO2 on pulm and systemic circulation
The opposite effect on pulm and systemic circulation
Low in PAO2
Hypoxic vasoconstriction that shifts blood away from poorly ventilated regions of lung to well-ventilated regions of lung.
Perfusion limited
O2 (normal health), CO2, N2O
Gas equilibrates early along the length of capillaries.
Diffusion can be increased only if blood flow increases.
Diffusion limited
O2 (emphysema, fibrosis) and CO
Gas does not equilibrate by the time blood reaches the end of the capillary.
Consequence of pulm HTN
Cor pulmonale and subsequent RV failure
JV distension, edema, hepatomegaly
Diffusion
Vgas=A/Tx Dk(P1-P2)
A=area
T=thickness
Dk(P1-P2) difference in partial pressure
A=decreased in emphysema
T= increased in pulm fibrosis