Pharm: H1 blockers Flashcards
1
Q
H1 blockers
A
Reversible inhibitors of H1 receptors
2
Q
1st generation: names
A
Diphenhydramine, dimenhydrinate, chlopheniramine
Names contain “-en/-ine” or “-en/-ate”
3
Q
1st generation: uses
A
Allergy, motion sickness, sleep aid
4
Q
1st generation: toxicity
A
Sedation, antimuscarinic, anti alpha adrenergic
5
Q
2nd generation: names
A
Loratadine, fexofenadine, desloratadine, cetirizine
Names usually end in “-adine”
6
Q
2nd generation: uses
A
Allergy
7
Q
2nd generation: toxicity
A
Far less sedating than 1st generation because of less entry into CNS.
