PUD Flashcards

1
Q

two categories

A

gastric
duodenal

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2
Q

Mgx

A

If h.pylori +ve - eradication therapy
Lifestyle
PPI (omerprazole)
H2 RA

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3
Q

Zollinger-ellison syndrome

A

Gastrinoma
In head of pancreas or duodenum
release gastrin
Causes stomach to produce more acid

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4
Q

H.pylori

A

colonises antrum
causes inflammation
Damages gastric mucosa
Forms ulcerations

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5
Q

NSAIDs

A

Inhibits COX 1
Decreases prostaglandins, which protect
Abrasions to stomach will be unable to heal
Pepsin can cause ulcerations

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6
Q

Smoking

A

Decreases prostaglandin synthesis

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7
Q

Ix

A

FBC
LFTs
Amylase
UGI endoscopy

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8
Q

H. pylori testing

A

Urea breath test
\Bloods - checks for IgG
Stool antigen
Urease

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9
Q
A
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