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Paper 1 > C.Diff > Flashcards

C.Diff Flashcards

1
Q

C.Diff bacterial characteristics

A

G +ve
Anaerobic

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2
Q

Risk factors

A

Pt taking Abx

  • disrupts competition in gut flora
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3
Q

What does C Diff produce?

A

Enterotoxins A & B

A = Enterotoxin
B = Cytotoxic - causes bloody diarrhoea

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4
Q

CFs

A

Diarrhoea +/- blood
Lower abd pain (colitis)
Nausea
Pyrexia
WCC count > 15 x 10^9
Raised lactate

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5
Q

Ix

A

XR Abdomen for toxic megacolon
Stool cultures

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6
Q

Mgx for mild/moderate C Diff

A

Metronidazole

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7
Q

Mgx for severe C Diff

A

Vancomycin

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8
Q

Mgx for non-responders to other therapies

A

high dose vancomycin, IV metronidazole, IV immunoglobulin

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9
Q

Mgx for recurring C Diff

A

Vancomycin
Foecal transplant

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10
Q

Acronym for suspected C Diff

A

SIGHT

Suspect
Isolate within 2 hrs
Gloves/aprons
Hand wash
Test

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Paper 1 (26 decks)

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