proteus/morganella/yersinia Flashcards

1
Q

characteristics of Proteus

A
  • non-lactose fermenter
  • motile with perichous flagella
  • “swarming” on agar surface
  • Urease producer
  • habitat: soil, water, intestinal tract of man and animals
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2
Q

what does urease do as a virulence factor?

A

-irritates mucus membrane in the ureters, bladder and the urethra

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3
Q

what does a Proteus mirabilis infections cause

A
  • UT infections in dogs and ponies
  • ear infections in dogs and cats
  • diarrhea in animals
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4
Q

characteristics of Morganella morganii

A
  • gram neg
  • facultatively anaerobic
  • rod-shaped
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5
Q

what does a Morganella morganii infection cause?

A

ear and UT infections in dogs and cats

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6
Q

bacteria responsible for bovine mastitis

A

-S. aureus
-Streptococcus
-E. coli
-Klebsiella pneumoniae
-Enterobacter aerogenes
-Proteus spp.
-Serratia marcescens
Others:
Pseudomonas aeruginosa,
Mycoplasma bovis, Mannheimia
haemolytica, Arcanbacterium
(Trueperella) pyogenes,
Pasteurella multocida,
Peptoniphilus indolicus,
etc.

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7
Q

are fungal or viral pathogens implicated in bovine mastitis?

A

both

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8
Q

how do most mastitic pathogens enter the mammary gland?

A

via the teat canal

-except mycoplasma: enters via the blood stream

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9
Q

what are the most cases of mastitis cause by? (5)

A
  • S. aureus
  • Strepto. agalactiae
  • S. dysgalactiae
  • S. uberis
  • E. coli
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10
Q

what are the primary reservoirs for contagious mastitis

A

infected mammary glands

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11
Q

what are the 3 major contagious mastitis pathogens

A
  • S. aureus
  • S. agalactiae
  • Mycoplasma
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12
Q

how to you get rid of mastitic pathogens?

A
  • postmilking germicidal teat disinfection

- antibiotic treatment of dry cows

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13
Q

what are the characteristics of Yersinia?

A
  • gram neg
  • rod-shaped
  • facultatively anaerobic
  • non-lactose fermenter
  • BIPOLAR STAINING (safety pin appearance
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14
Q

what are the 3 important species of Yersinia?

A
  • Y. pestis (human plague; cats)
  • Y. pseudotuberculosis (guinea pigs)
  • Y. enterocolitica (enteritis in humans, food-borne)
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15
Q

what entericYersinia reside in the intestinal tract and are associated with enterocolitis in animals and humans?

A
  • Y. pseudotuberculosis

- Y. entercolitca

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16
Q

what are the modes of infections of Yersinia

A
  • flea bites
  • inhalation
    • contact with infected or dead animals
  • cat bites
  • ingestion (in cats)
17
Q

what mode of infection of Yersinia infects dogs and cats

A
  • ingestion of infected rodents
  • rodent bites
  • fleas
18
Q

what is sylvatic plague?

A

plague in rodents

  • serve as maintenance hosts
  • transmitted by fleas
  • source of infection to animals and humans
19
Q

what are the virulence factors for Yersinia

A
  • Fraction 1 protein
  • V and W antigens
  • Murine toxin
  • LPS (fever, vascular damage, DIC)
  • Pesticin
  • (hyaluronidase, coagulase etc)
20
Q

what is Yersiniabactin?

A

a siderophore that allows it to have the ability to acquire iron

21
Q

what disease does Yersinia cause?

A
  • bubonic plague

- pneumonic plague (black death)

22
Q

what animals are most susceptible to the plague?

A

cats

23
Q

what is feline plague

A
  • link between rodent plague and human infections
  • acquire by ingestion of infected rodents
  • 3 forms: bubonic, septicemic, and pneumonic
24
Q

what are the clinical signs of feline plague

A

fever, depression, anorexia, swollen LN

25
Q

what is the treatment to feline plague

A
  • bubonic form may respond to antibiotic therapy
  • streptomycin
  • tetracyclines or chloramphenicol
26
Q

what is the habitat of Y. enterocolitica

A
  • GI tract and Ln of animals -pigs

- in the tonsils of healthy pigs

27
Q

what are the virulence factors of Y. enterocolitica

A
  • enterotoxin

- stimulation of guanylate cyclase activity

28
Q

what are 5 food-borne pathogens?

A
  • S. aureus
  • E. coli O157:H7
  • Salmonella Typhimurium
  • Cronobacter sakazaki
  • Yersinia enterocolitica
29
Q

Yersiniosis

A

-Stress is a predisposing the factor.
-Clinical signs: Diarrhea (no
blood)
-Enterocolitis: Jejunum and ileum
are most frequently affected.
-May become systemic (miliary
abscesses).

30
Q

what is Y. ruckeri

A
  • fish pathogen
  • enteric ‘ Red Mouth’ disease
    • SubQ hemorrhage aroudn the mouth