Proteins Of The Complement System (Classical Pathway) Flashcards by Rae Anne Montealegre | Brainscape

Q

Binds to Fc region of IgM and IgG

A

C1q

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Q

Activates C1s

A

C1r

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Q

Cleaves C4 and C2

A

C1s

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Q

Part of C3 convertase (C4b)

A

C4

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Q

Binds to C4b; forms C3 convertase

A

C2

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Q

Key intermediate in all pathways

A

C3

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Q

Initiates membrane attack complex

A

C5

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Q

Binds to C5b in MAC

A

C6

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Q

Binds to C5bC6 in MAC

A

C7

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Q

Starts pore formation on membrane

A

C8

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Q

Polymerizes to cause cell lysis

A

C9

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