ASO Agglutination Test Flashcards
ASO
Anti-streptolysin O
streptococci characteristics
gram positive spherical, ovoid, lancet shaped organism
catalase negative that are often seen in pairs or chains under microscope
what is the basis of the division of streptococci into different serogroups?
cell wall components
what major proteins are contained on the outermost cell wall components?
M and T protein
these determine the serotype or serogroup of the streptococcus spp.
M and T protein
interior to the protein layer that divides streptococci into 20 defined groups
group-specific carbohydrate
20 defined groups of streptococci
A-H, K-V
some biologically important streptococcus belong to what groups
group A, B, C, D
group of s. pyogenes
group A
group of s. galactiae
group B
group of s. dysgalactiae
group C
group of s. bovis
group D
group of enterococcus
group D
one of the most common and ubiquitous pathogenic bacteria and causes a variety of infection
s. pyogenes
diseases caused by s. pyogenes
scarlet fever, bacterial acute glomerulonephritis, acute rheumatic fever
what is the major virulence facto of s pyogenes of group A?
m protein
what is the function of m protein
inhibits phagocytosis by inhibiting adhesion process
other virulence factors of s pyogenes
exotoxins
responsible for the rash seen in scarlet fever and also appear to contribute to pathogenicity
pyrogenic exotoxins A, B, and C
enzymes produced by streptococcus
streptolysin O, DNAse B, hyaluronidase, NADase, streptokinase
the most diagnostically important antibodies
ASO, anti-DNAse B, anti-NADase, anti-hyaluronidase
Group A streptococcus infection is seen in conditions like
scarlet fever, acute glomerulonephritis, acute rheumatic fever, necrotizing fasciitis, streptococcal shock syndrome
what is the principle of ASO agglutination test
passive agglutination in which antigen is accompanied by a carrier particle
what does the ASO agglutination test detect?
antibody
