Deficiencies of Complement Components Flashcards

1
Q

Lupuslike syndrome; recurrent infections

A

C1 (q, r, s)

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2
Q

Lupus-like syndrome
Recurrent infections
Atherosclerosis

A

C2

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3
Q

Severe recurrent infections
Glomerulonephritis

A

C3

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4
Q

Lupuslike syndrome

A

C4

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5
Q

Neisseria infections

A

C5-C8

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6
Q

No known disease association

A

C9

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7
Q

Hereditary angioedema

A

C1INF

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8
Q

Paroxysmal nocturnal hemoglobinuria

A

DAF
MIRL

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9
Q

Recurrent pyogenic infections

A

Factor H
Factor I

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10
Q

Pneumococcal diseases, sepsis, Neisseria infections

A

MBL

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11
Q

Neisseria infections

A

Properdin

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12
Q

Pneumococcal diseases

A

MASP-2

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