Proteins Flashcards
What does it contain
Carbon oxygen nitrogen sulfur hydrogen
Describe or draw general structure of amino acids
- Alpha carbon
- Radical group
- Carboxylic group
- Amine group
What reaction does it undergo and what bond
Condensation reaction and makes a peptide bond
What is the primary structure
Sequence of amino acids in polypeptide
What is the secondary structure
Cooking or folding of polypeptide chain (held together by hydrogen bonds)
What is the tertiary structure
Further coiling and folding and gives it a 3d final shape of the protein
What are the 4 bonds it is held by
Hydrogen bond, disulfide bond, ionic and hydrophobic and hydrophilic attraction
What is a polypeptide
Long chain of amino acids linked by peptide bonds
What determines the function of polypeptide
It’s structure of amino acid sequence
Why does properties of each amino acid affect the properties of polypeptide
Different properties have affect on sequence and therefore impact sequence (different types of bond)
Globular protein examples
- Haemoglobin
- Insulin
- Catalase
Haemoglobin
4 polypeptide chains contains prosthetic haem which contains fe2+
Water soluble
Can reversibly bind o2
Hold up to 4 o2 molecules
Insulin
Two polypeptide chains
Specific shaped quaternary structure to bind to receptor
Soluble
Allows it to bind to complementary receptors on cell surface causing glucose to be transported
Catalase
4 polypeptide chains with fe2+
Specific 3d quaternary structure
Soluble
Active site is complementary to substrate
Interacts with h2o2 to break it down
Fibrous proteins examples
Keratin
Collagen
Elastin
