protein structure- lqc 1a

Question 1

definition of primary structure of a protein

Answer 1

The specific sequence of amino acids in a polypeptide chain, formed by condensation reactions

Question 2

definition of secondary structure of a protein

Answer 2

Formed when amino acids interact to form an alpha helix or a beta pleated sheet

Question 3

definition of tertiary structure of a protein

Answer 3

Further folding of the secondary structure into a specific 3D shape- Held together by bonds between amino acid R groups

Question 4

definition of quaternary structure of a protein

Answer 4

Three-dimensional arrangement involving more than one polypeptide chain

Question 5

what bonds are formed in a primary structure of a protein

Answer 5

peptide

Question 6

what bonds are formed in the secondary structure of a protein

Answer 6

hydrogen

Question 7

what bonds are formed in the tertiary structure of a protein

Answer 7

hydrogen, ionic, disulphide

Question 8

what bonds are formed in a quaternary structure of a protein

Answer 8

hydrogen, ionic, disulphide

Question 9

where you would find the polar R groups in a protein.

Answer 9

Outside/on the surface of the protein

Question 10

Explain where you would find the non-polar R groups in a protein.

Answer 10

Inside of the protein

Question 11

Explain the importance of a protein’s primary structure in determining its 3D structure.

Answer 11

The primary structure (order/sequence of amino acids in polypeptide chain), determines the position of amino acid R groups. Hydrogen , ionic and disulphide bonds can form between these R groups. These bonds determine how a polypeptide chain folds into a specific 3D shape, forming a protein.

Question 12

what happens in a secondary structure of a protein

Answer 12

Hydrogen bonds form between the slightly negative C=O of the carboxyl group and the slightly positive N-H of the amino group of different amino acids. Not between R groups.

Question 13

what is a tertiary structure of a protein held together by

Answer 13

Held together by bonds between amino acid R groups

Question 14

why would you find polar R groups on the outside/surface of a protein

Answer 14

They are hydrophilic therefore they are attracted to other polar molecules

Question 15

why would you find non polar R groups on the inside of a protein

Answer 15

They are hydrophobic therefore they repel other polar molecules like water

Question 16

what does the specific 3D shape of a protein do

Answer 16

The specific 3D shape of a protein gives the protein specific properties and allows it to carry out a specific function .