Prostate and Kidney Cancer

Question 1

Name the risk factor of prostate cancer (4)

Answer 1

> 50 y/o
Black
Obesity
FHx

Question 2

T/F: Prostate cancer is the most common cause of cancer in men and the 5th most common cause of death.

Answer 2

False. 2nd most common cause of death. Rest of statement is true.Mortality has decreased over the years though.

Question 3

T/F: High % free PSA is a sign of prostate cancer.

Answer 3

False. Low % free PSA. High PSA

Question 4

All of the following could result infalsepositive PSA EXCEPT:
A. Cystoscopy
B. BPH
C. Recent ejaculation
D. DRE
E. Prostatitis

Answer 4

D

Question 5

Who should we screen?
A. Men b/w 45-54 y/o with average risk
B. Men > 70 y/o
C. Patients with lower urinary tract symptoms
D. Men b/w 55-69 with average risk

Answer 5

C

D. Considered “shared decision making”

Question 6

Prostate cancer is diagnosed by ____

Answer 6

Trans-rectal ultrasound-guided biopsy (TRUS)

Question 7

The most common type of prostate cancer is ____ and arise in the ____ zone.

Answer 7

adenocarcinoma (95%)

Peripheral

Question 8

T/F: Therapy for low risk localized prostate cancer is brachytherapy.

Answer 8

False.
Avoid therapy w/ low risk prostate cancer.
Monitor with PSA, DRE, prostate biopsy.

Question 9

T/F: Prostate cancer is cured by radical prostatecomy.

Answer 9

False. There is no curative treatment.

Question 10

85-90% of all primary renal neoplasms are ____

Answer 10

Renal cell carcinoma

RCC until proven otherwise

Question 11

Which of the following is NOT on the differential for solid renal mass?
A. Renal cell carcinoma
B. Squamous cell carcinoma
C. Oncocytoma
D. Angiomyolipoma
E. Urothelial carcinoma

Answer 11

B

Question 12

Von-Hippel Lindau =

Answer 12

Risk factor of kidney cancer

Genetic syndrome:
Cereberallar hemangio-blastoma
Retinal angiomas
Renal cysts
Clear renal cell cancer
Epidiymal cystadenoma
Pancreatic cysts
Pheochromocytoma

Question 13

Name the classic triad of symptoms of renal carcinoma

Answer 13

Flank pain
Palpable mass
Hematuria

*only 10% of pts present this way…so much for classic

Question 14

Kidney cancer can present with paraneoplastic syndrome. Which of the following is NOT part of the syndrome?
A. Hypocalcemia
B. Erythrocytosis
C. HTN
D. Fever
E. Neuromyopathy

Answer 14

A.Hypercalcemia

Also:Anemia, Cachexia

Question 15

Preferred imaging modality in assess kidney cancer

Answer 15

CTwithcontrast

Question 16

T/F: Renal biopsy should be performed when suspected lymphoma, large (>40 cm) renal tumors or metastatic disease.

Answer 16

False. Unnessary for large renal tumors. Perform for small tumors (

Question 17

T/F: Treatment is primarily medical for localized kidney disease.
Preferred method(s)?

Answer 17

False. Primarily surgical.

Laparoscopic nephrectomy
Partial nephrectomy for select patients

Question 18

T/F: Metastatic renal cancer is treatable with chemo and radiotherapy with good prognosis.

Answer 18

False. Poor prognosis.
Resistant to chemo and radiotherapy
Treat with immunotherapy