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Knowledge Rehab > Cervical and Endometrial Cancer > Flashcards

Cervical and Endometrial Cancer Flashcards

1
Q

Pap smears reduce incidence of cervical cancer by 70%.

Cerivcal cancer is the #2 cause of cancer death in women.

A

Freebie! There was no question. Good way to start off a new deck. =)(FYI, It’s a true statement)

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2
Q

T/F: Getting a HPV infection means that you will get cervical cancer in the future.

A

False. Getting HPV infection doesn’t mean you’ll get cervical cancer. HPV infection is VERY prevalent but will resolve within 2 years in young immunocompetant patients.

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3
Q 
All of the following are risk factors for oncogenic HPV EXCEPT:
A. Smoking
B. Immunocompetance
C. Early age at 1st time sex
D. Low socioeconomic status
A

B. Immunocompromisedis most important risk factor

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4
Q

Most common histological type of cervical cancer

A

Squamous cell carcinoma (80%)Adenocarcinoma = #2 most common

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5
Q

Which HPV strain(s) seen in 90% of adenocarcinoma cerival neoplasia?

A

HPV 16 and 18

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6
Q

What is the recommendation of immunization against HPV?

A

vaccinate w/ nonavalent aged 11-12 for girls AND boys, catch up to 26

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7
Q

What is the cervical cytologic screening recommendation?

A

Initial screening start at 21 y/o

Repeat cytology q 3 years b/w 21-65 y/o

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8
Q

T/F: HPV testing is indiciated in adolescents.

A

False. Unnecessary since 90% of HPV infections naturally resolve within 2 years.

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9
Q

T/F:1-2 year persistence of HPV 18predicts 20-30% of CIN 3+ over 10years

A

False. HPV 16

5 years

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10
Q

Initial presenting symptoms of cerival cancer (2)

A

Abnormal bleeding

Unusual vaginal discharge

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11
Q

T/F: A diagnosis of cervical cancer is made by a positive cervical cytology.

A

False. Must confirm with biopsy.Cervical cytology is used for screening. When tumor is clinically visible, only need biopsy.

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12
Q

Most common histological type of cervical cancer

Pattern of spread?

A

Squamous cell carcinoma

Local invasion, lymphatic spread

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13
Q

Types of cervical cancer that spreads hematogenously (3)

A

Adenocarcinoma
Neuroendocrine
Small cell tumors

= worse prognosis

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14
Q

T/F: Staging of cervical cancer is based on surgical evaluation.

A

False.Exclusively based on clinical evaluation
Does NOT change based on findings post surgery
Allows staging to occur in low resource settings

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15
Q

Treatment of early stage cervical cancer

A

Radical hysterectomy w/ pelvic lymph node dissection (PLND)
OR
Primary chemotherapy

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16
Q

Treatment of locally advanced stage cervical cancer

A

Primary chemoradiation

17
Q

Treatment of distant metastases (4B) cervical cancer

A

Systemic chemotherapy

18
Q

Radical trachelectomy =

Used when?

A

Removal of cervix alone

Used to preserve fertility in women with cervical cancer

19
Q

Post cervical treatment follow-up schedule

A 
PAP yearly
CXR yearly
Clinical evaulation:
Q 3 months x 2 years
--> Q 6 months x 3 years
--> Annually
20
Q

T/F: Endometrial cancer is the most common gynecologic cancer and has a high mortatality.

A

False. Most common buthigh surivivald/t early diagnosis

21
Q

T/F: Endometrial cancer is most common young white women.

A

False. White old women
Black women also at (lesser) risk
Peak age: 60-70

22
Q

Type 1 endometrial cancer =

A

Estrogen dependent
Endometrioid adenocarcinomas
Better prognosis

23
Q

Type 2endometrial cancer =

A

Non-estrogen dependent
Papillary serous
Clear cell
Worseprognosis

24
Q

Most common clinical symptom of endometrial cancer

A

Post menopausal bleeding

25
Q

T/F:Endometrial Hyperplasia/Endometrial Intraepithelial Neoplasia (EIN) is precursor to endometrial cancer. The highest risk is with complex atypical hyperplasia.

A

True

26
Q

Highly sensitive work up for endometrial cancer

A

Endometrial biopsy +/ transvaginal US

27
Q

T/F:Staging of endometrialcancer is based on surgical evaluation.

A

True

28
Q

T/F: Postiive nodes changes staging from 2 to 3 in endometrial cancer.

A

True

Unlike cervical cancer where staging does not change post surgery

29
Q

Most important prognostic factor of endometrial cancer

A

Lymph node metastasis

30
Q

Treatment of primary endometrial cancer

A

Hysterectomy +/- Pelvic and paraortic lymph node dissection (PPLND)

31
Q

Post endometrial treatment follow-up schedule

A 
Clinical exam Q 3-4 months x 2 years
Clinical exam Q 6 months x 3 years
Yearly after 5 years
CXR yearly
Pap smear not required
32
Q

T/F: Endometrial cancers are more likely to reoccur than cervical cancer within 2 years.

A

False. Cervical cancer more likely to recur (80%) than endometrial cancer (50%)

33
Q

T/F: Cervical cancer recurrence is harder to treat than endometrial cancer recurrence.

A

True. 80% of endometrial cancer recurrence are treatable vs 20% in cervical cancer

Knowledge Rehab (24 decks)

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