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Gynaecology > Prolactinoma > Flashcards

Prolactinoma Flashcards

1
Q

What is prolactinoma?

A

A tumour of the pituitary gland that secretes excessive prolactin

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2
Q

What is a microadenoma?

A

A pituitary adenoma less than 1cm

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3
Q

What is a macroadenoma?

A

A pituitary adenoma larger than 1cm

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3
Q

What are the features of excess prolactin in women?

A

Amenorrhoea
Galactorrhoea
Infertility
Osteoporosis

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3
Q

What are the general features of a pituitary adenoma?

A

Headache
Visual disturbance - bitemporal hemianopia or upper temporal quandrantanopia
Signs of hypopituitarism

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3
Q

What is the definitive investigation in the diagnosis of prolactinoma?

A

MRI
Serum prolactin

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4
Q

What are the differentials of prolactinoma?

A

Drug induced hyperprolactinaemia
Primary hypothyroidism
Pregnancy
Non-functioning pituitary adenoma

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5
Q

What is the first line management for a symptomatic prolactinoma?

A

Dopamine agonists

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6
Q

What dopamine agonists are commonly given for prolactinoma?

A

Carbergoline
Bromocriptine

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7
Q

What is the second line management for prolactinoma?

A

Trans-sphenoidal adenoma resection

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Gynaecology (27 decks)

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