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Gynaecology > Premature ovarian insufficiency > Flashcards

Premature ovarian insufficiency Flashcards

1
Q

What is premature ovarian insufficiency?

A

Menopause before 40 years

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2
Q

What will hormonal analysis show in someone with premature ovarian insufficency?

A

High FSH
High LH
Low oestradiol

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3
Q

What is the main cause of premature ovarian insufficency?

A

50% of cases are idiopathic

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4
Q

What are the other causes of premature ovarian insufficency?

A

Iatrogenic
Autoimmune
Genetic
Infections

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5
Q

What is the presentation of premature ovarian insufficiency?

A

Irregular menstrual periods
Hot flushes
Night sweats
Vaginal dryness
Infertility

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6
Q

What level of FSH is indicative of premature ovarian insufficency?

A

FSH> 40

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7
Q

How is premature ovarian insufficency diagnosed?

A

Two FSH levels > 40 taken 4-6 weeks apart

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8
Q

What are the complications of premature ovarian insufficency?

A

Cardiovascular disease
Osteoporosis
Cognitive impairment
Dementia
Parkinsonism
Stroke

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9
Q

What is the management of premature ovarian insufficency?

A

HRT until age 51

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Gynaecology (27 decks)

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