PROKINETICS Flashcards
1
Q
cholinomimetic agents:
A
- bethanechol
2. neostigmine
2
Q
dopamine D2-receptor antagonists:
A
- metoclopramide
2. domperidone
3
Q
mechanism of action of bethanechol:
A
stimulate muscarinic M3 receptors on muscle cells
4
Q
mechanism of action of neostigmine:
A
acetylcholinesterase inhibitor
5
Q
mechanism of action of metoclopramide & domperidone:
A
- increase esophageal peristaltic amplitude
2. increase lower sphincter pressure → enhance gastric emptying