problems Flashcards
gestational diabetes when
20wks on
foetus can make mother insulin resistant. which hormones does the baby make
hPL PCRH making cortisol and PGH
pregnancy is a naturally …resistant state. why?
insulin
excess glucose is what foetus needs for growth
is gestational dm more like type 1 or 2
a mixture of both. insulin production is restricted from beta cells AND insulin resistance
increased cortisol leads to …resistance
insulin
massive baby might need what when it’s born
glucose drip to wean off hyperinsulinemia
perinatal hypoglycemia
meds for gestational dm
metformin glyburide
what levels of hepcidin in different stages of prg
Up in 1st trimester
Down in 2nd and 3rd trimester
when is gestational anemia more common
2 and 3 trimester
when is amniotic fluid most. how much
28 wks 800ml
what condition oligohydramnios. why?
Potter sequence - flat face, squished face, club foot
normally kidney abnormalities
cytomegalovirus what is it
generic sub-clinical virus but can be dangerous if mum catches primary infection in 1st trimester, 10% of asymptomatic babies and 90% of symptomatic babies have hearing probs (sensory neural deafness), mental retardation, microcephaly
what is the biggest cause of hearing loss in young children
cytomegalovirus
symptomatic baby CMV how does it look
petechial purpuria with jaundice
classic triad of gestational rubella
cardiac. cataract/glaucoma, deafness
cardiac probs:
patent ductus arteriosus, pulmonary valve stenosis
gestational toxoplasmosis
Chorioretinitis , hydrocephalus, intracranial atherosclerosis
mortality in untreated neonate herpes
65%
what sort of bateria is listeria
gram+ rod
congenital syphilis sequelae
Early 0-2 years
Rash
Rhinorrhoea (mucus full of T.pallidum)
Osteochondritis
Perioral fissures
Lymphadenoapthy
Pemphigus syphiliticus
Late >2 years
Hutchinson’s teeth
Clutton’s joints
Saber shins
High arched palate
Deafness
Saddle nose deformity
Frontal bossing
foetus makes what molecule -> Hyperemesis gravidarum
GDF15
which vitamin for morning sickness, when
B6 from point of conception
which is the only viable aneuploidy
Turner’s (X0)
inevitable miscarriage ultrasound
gestational sac is completely detached
recurrent miscarriage
3 or more consecutive miscarriages
where should pregnancy implant
top back wall
Placenta abruption
Placental praevia
Incidental genital tract pathology
Uterine rupture
Vasa praevia
Fetal blood vessels run close to or over opening of the uterus
symptoms of placental abruption
bleeding
tense woody uterus
weak or absent fetal heartrate
what is placental abruption
retroplacental blood clot
placenta praevia tx
lower segment C section
describe the placenta accreta etc problems
what is pre-eclampsia
hypertension after 20 wks, proteinuria, low placental growth factor
in pre-eclampsia, what happens to the spiral arteries
stay narrow so blood is under high pressure, baby gets much less O2