Prion Disease Flashcards
1
Q
What is it?
A
Protein-only infectious agent
2
Q
Where is the gene for PrP protein found?
A
Chr20 -expressed in CNS
3
Q
Prion disease differentials
A
Huntington’s, spinocerbellar ataxia, dementia, MS, psych
4
Q
Prion disease Mx
A
untreatable
Sympoms - clonazepam
Delaying conversion - quinacrine, pentosan, tetracyclin
5
Q
Summarise Ix findings for CJD types
A
6
Q
Summarise Sporadic CJD
A
7
Q
Summarise Acquired CJD
A
8
Q
Summarise congenital CJD
A
