Hepatitis Flashcards
IgM +, IgG -
Acute infection
IgM -, IgG +
Previous infection or vaccination
HBsAg+, Anti-HBc+, IgM Anti-HBc+, Anti-HBs-
Acute Hepatitis B infection
HBsAg+, Anti-HBc+, IgM Anti-HBc-, Anti-HBs-
Chronic Hepatitis B infection
HBsAg-, Anti-HBc+, IgM Anti-HBc-, Anti-HBs+
Past Hepatitis B infection
HBsAg-, Anti-HBc-, IgM Anti-HBc-, Anti-HBs+
Hep B Vaccination
Anti-HCV-, HCV RNA+
Acute Hep C Infection
Anti-HCV+, HCV RNA+
Chronic Hep C Infection
Anti-HCV+, HCV RNA-
Past Hep C Infection
Anti-HEV IgM+, Anti-HEV IgG-
Acute Hep E Infection
Anti-HEV IgM-, Anti-HEV IgG+
Past Hep E Infection
Two main HBV antigens
Surface (s)
Core - in the capsule (c)
GS for active HBV diagnosis
HBsAg
Threshold for Hep B chronic infection
HBsAg persistent after 6 months
Why is only Anti-HBs positive in vaccinated people whereas in past infection, Anti-HBc is also positive
The vaccine only contains HBs