Primary sclerosing cholangitis

Question 1

Differentiate between this and PBC

Answer 1

PSC is inflammation of BOTH intra and extrahepatic bile ducts, whereas primary biliary cholangitis is due to inflammation and obstruction of intrahepatic bile ducts only

Question 2

Consequence of PSC

Answer 2

Cholangiocarcinoma

Question 3

Rx

Answer 3

ULCERATIVE COLITIS

FH

Question 4

Symptoms

Answer 4

Can be asymptomatic 
Jaundice
Pruritis
Episodes of bacterial cholangitis 
RUQ pain
Fatigue/weight loss
Symptoms of cirrhosis

Question 5

Why do you get bacterial cholangitis and WHERE

Answer 5

(due to build up of bile in common bile duct)

Charcot’s triad