Crohn's Flashcards

1
Q

Risk factors

A

Smoking
Oral contraceptive pill
Nutritional deficiency
Previous infection

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2
Q

Which part of the GI is affected?

A

Entire GI tract, transmural

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3
Q

Epidemiology

A

Two peaks: 20-40 years and 60-70 years

Caucasian ethnicity

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4
Q

Are they always unwell?

A

Yes, systemically unwell

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5
Q

What kind of lesions are seen in Crohns?

A

Patchy skip lesions

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6
Q

What is common in Crohns but not in UC?

A

Abscesses/fissures

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7
Q

Most common site that’s affected?

A

Terminal ileum

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8
Q

Symptoms?

A

Bloody diarrhoea that’s MIXED

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9
Q

Where is the pain?

A

RIF

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10
Q

Any other symptoms?

A

Fever

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11
Q

Signs

A

Perianal lesions

Crohn’s

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12
Q

Investigations

A
Stool sample (H pylori)
Blood tests (CRP, ESR)
CT/MRI of abdomen 
Colonscopy and biopsy
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13
Q

Management

Inducing remission

A

Corticosteroids

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14
Q

Maintaining remission

A

Azathioprine
Methotrexate
Cyclosporin
Methotrexate

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