Previous paper Qns Flashcards

1
Q

Name some drugs of BCS class III

A

Acyclovir, Atenolol, Captopril

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2
Q

What is meant by ‘Dwell time’ in the compression of tablets?

A

Time it takes for the punches to stop moving vertically and to achieve maximum penetrative in the die under the primary compression rollers

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3
Q

Spin quantum number of ¹³C NMR is…

A

1/2

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4
Q

What is the starting material for the synthesis of Lignocaine?

A

2, 6 - Xylidine

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5
Q

Rancidity value is determined by…

A

Peroxide value

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6
Q

Bloom strength is directly proportional to…

A

Molecular weight

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7
Q

When is the best time to collect a medicinal bark?

A

After the leaf falls

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8
Q

Name a specific category of anti-biotics which undergo light catalyzed auto-oxidation

A

Polyene antibiotics

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9
Q

What type of rheological behaviour of fluid is ‘time independent’?

A

Anti-thixotropic

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10
Q

Name the diagnostic test for Syphillis

A

Kahn’s test

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11
Q

Diagnostic test for AIDS

A

ELISA

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12
Q

Equivalent weight of KMnO4 in acidic solution

A

31.6

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13
Q

Which zone is dry and hot?
Zone I
Zone II
Zone III
Zone IV

A

Zone III

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14
Q

What is the composition of Lindlar catalyst?

A

Palladium and CaCO3

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15
Q

Alfa Alfa belongs to which family?

A

Leguminosceae

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16
Q

Name an Anti-oxidant obtained from a desert plant, which shows synergistic action with citric acid

A

Nor de-hydro guaiaretic acid (NDGA)

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17
Q

Which volatile oil is heavier than H20?

A

Cinnamon oil

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18
Q

How many AA are present in H1 receptor protein?

A

487 AA

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19
Q

Name the ionisation technique most useful for large biomolecules like proteins

A

Electrospray Ionisation (ESI)

20
Q

M.O.A of Metformin

A

It acts by increasing the levels of INCRETIN hormone by inhibiting the enzyme Di-peptidyl peptidase 4 (DPP-4)

21
Q

The etiology of Jaundice could be HEMOLYTIC ANEMIA if….

A

Unconjugated bilirubin = Conjugated bilirubin

22
Q

Biological activity of Synthetic Adrenaline = _________

A

25% (S - Adrenaline)

23
Q

Murmurs are disorders involving the….

A

Pulmonary vein

24
Q

Tetracycline undergoes epimerization at C4 in the pH 4-8 to give….

A

Iso-tetracycline

25
What kind of a disease is Leprosy?
Fungal disease
26
Type III hypersensitivity is ________
Cell-mediated or delayed hypersensitivity
27
As per Brownsted Lowry theory, an acid is a...
Substance or molecule which donates a proton
28
Aerobic dehydrogenase in biological oxen. contains....
FMN or FAD
29
Plasma protein bound drugs are ____________ inert
Pharmacodynamically
30
What is the chemical name of SPIRIT OF SALT
HCl
31
Name a short acting Anti-ChE drug
Edrophonium
32
Who proposed the theory that, "In general anesthetics, chain length is directly proportional to lipid solubility and anesthetic potency"?
Mayer Overton
33
Which immunoglobulin can cross the placenta?
IgG
34
Which antibody is dominant in immune responses
IgM
35
Causative organism for Syphillis
Treponema palladum
36
What is the outer covering of Testes called?
Tunica vaginalis
37
What is the optimum temperature for the rapid growth of mesophils?
25 - 40°C
38
Name the most common neoplasm in people with AIDS
Kaposi sarcoma
39
Coomb's test is used for the detection of...
Anti-globulin
40
Which nerve is important for motor functions?
Accessory cranial nerve
41
What is Transduction?
Virus mediated transfer of host DNA from one cell to another
42
Name the best technique for detecting HIV
Reverse transcriptase PCR
43
What will the LOG P value of an ideal candidate for TRANSDERMAL PERMEATION be?
1-3
44
M.O.A of Artemesinin
They act by generating ROS by the cleavage of enderoperoxide bridge, leading to the death of the parasite
45
Which cranial nerve regulates heart beat?
Cranial nerve X
46
In the process of drying, Adiabatic saturation temperature is same as....
Wet bulb temperature