Pressure and Flow in Arteries and Veins Flashcards
How does pressure change through arteries?
Falls slightly 95mmHg to 90mmHg
How does pressure change through arterioles?
Drops from 90 to 40mmHg
What is the pressure difference pushing blood back through veins?
20 to 5mmHg
What is the pressure in the pulmonary circulation?
1/5th of systemic
What is meant by pulse pressure?
Difference between systolic and diastolic pressure
What is the respiratory pump?
Increased resp rate and depth increase venous return and edv
What are the anti clotting mechanisms of the endothelium?
Stops blood contacting collagen
Produces prostacyclin and NO (inhibit platelet aggregation)
Produces tissue factor pathway inhibitor (stops thrombin)
Expresses thrombomodulin (inactivates thrombin)
Expresses heparin
Secretes tissue plasminogen activator (plasminogen->plasmin and digests clot)