Pregnancy Flashcards

1
Q

how long is the menstrual cycle normally?

A

28 days long

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2
Q

when does the menstrual cycle begin?

A

menstruation

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3
Q

what are the two phases of the menstrual cycle?

A

follicular phase

luteal phase

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4
Q

what is the first half of the menstrual cycle called?

A

follicular phase

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5
Q

what happens in the follicular phase?

A

ovum develops in the follicle

oestrogen produced by the follicle

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6
Q

when does LH peak?

A

at around 14 days

just before ovulation

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7
Q

what happens to the follicle after ovulation?

A

becomes the corpus luteum

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8
Q

what is the second half of the menstrual cycle called?

A

the luteal phase

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9
Q

what does the luteum do?

A

grows and produces progesterone

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10
Q

what happens if fertilisation does not occur?

A

the luteum dies off

menstrual cycle starts again

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11
Q

what hormone does the ovum produce?

A

oestradiol

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12
Q

what hormone does the corpus luteum produce?

A

progesterone

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13
Q

what hormone does the implanted zygote produce?

A

HCG

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14
Q

what hormone is picked up by a pregnancy test?

A

HCG

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15
Q

what three hormones are produced by the placenta?

A

human placental lactogen (HPL)
placental progesterone
placental oestrogens

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16
Q

what causes insulin resistance in a pregnant mother?

A

placental progesterone

HPL

17
Q

what are the three types of diabetes found in pregnancy?

A

type 1
type 2
gestational

18
Q

what is gestational diabetes?

A

diabetes that comes on during pregnancy and will go away after

19
Q

when does foetal organogenesis start?

A

5 weeks gestation

20
Q

what are some complications associated with T1 and T2Dm in pregnancy?

A

malformation
prematurity
IUGR

21
Q

what are some complications associated with all types of diabetes in pregnancy?

A

macrosomia
polyhydramnios
intrauterine death

22
Q

what is macrosomia?

A

baby >90th centile for size

23
Q

what is polyhydraminos?

A

increased amniotic fluid around the baby

24
Q

name three possible complications that can affect babies of diabetic mothers after birth

A

respiratory distress
hypoglycaemia
hypocalcaemia

25
what should be prescribed for all diabetic women who become pregnant?
folic acid 5mg at least 3 months prior to conception if possible
26
when are eye checks done in pregnancy for diabetic patients?
every 10 weeks 20 week check can be skipped if week 10 clear
27
what medications can be given for blood pressure in pregnancy?
labetalol nifedipine methyldopa
28
what blood pressure drugs should be avoided in pregnancy?
ACEi | statins
29
what medication should be started in all high risk pregnancies and why?
aspirin 150mg at 12 weeks reduces risk of pregnancy induced hypertension
30
what should be done in the post-natal period for someone with gestational diabetes?
6 week post natal fasting glucose or OGTT to ensure resolution of diabetes
31
what impact can thyroid disease have on fertility?
result in anovulatory cycles
32
what are anovulatory cycles?
menstrual cycles without ovulation
33
what is maternal thyroxine important for during foetal development?
development of the CNS
34
what should be done for patients on levothyroxine if they become pregnant?
dose should be increased ASAP
35
what effect does HCG have on thyroid hormones?
suppresses TSH | causes high T4
36
what does high HCG cause?
hyperemesis
37
what anti-thyroid drugs can be used in pregnancy?
propylthiouracil in semester 1 carbimazole in the others