Pituitary Physiology Flashcards
what does excess gonadal hormones act on?
the hypothalamus
what does excess cortisol act on?
the pituitary
what three things can cause endocrine presentations?
too much hormone
too little hormone
gland is too large
what are the pituitary and peripheral steroid hormones?
ACTH
cortisol
what are the pituitary and peripheral thyroid hormonens?
TSH
thyroxine
what are the pituitary and peripheral sex hormones?
LH/FSH
testosterone/oestradiol
what are the pituitary and peripheral growth hormones?
GH
IGF-1
what are the pituitary and peripheral prolactin hormones?
prolactin only
what can a pituitary adenoma growing upwards cause?
compression of the optic chiasma
what can a pituitary adenoma growing laterally grow into?
the cavernous sinus
what stimulation test is done to test cortisol levels?
synacthen test
what is a normal response for a synacthen test?
cortisol rises by 150 and reaches 500
how is GH deficiency investigated?
insulin stress test/prolonged glucagon test
what is involved in the insulin stress test?
glucose given
cortisol and GH response measured every 30 mins for 2-3 hours