Basics Flashcards

1
Q

what are the three basic hormone subtypes?

A

proteins/peptides
amino acid derived
lipid derived

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2
Q

what is the most diverse class of hormones?

A

proteins and peptides

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3
Q

name three peptide hormones

A

insulin
GH
prolactin

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4
Q

name two amino acid derived hormones

A

adrenaline

melatonin

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5
Q

name two lipid derived hormone

A

testosterone

oestradiol

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6
Q

what is another name for lipid derived hormones?

A

steroid hormones

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7
Q

what type of receptor is the insulin receptor?

A

receptor tyrosine kinase activity

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8
Q

what type of receptor is the prolactin or growth hormone receptor?

A

cytokine receptor

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9
Q

what is the major determinant of hormone concentration?

A

rate of secretion

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10
Q

what is done to assess thyroid hormones?

A

highly sensitive TSH assay

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11
Q

what characterises sick euthyroid syndrome?

A

low free T3/4

inappropriate low/normal TSH

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12
Q

why is random cortisol measurement of little value?

A

secreted in a circadian pattern

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13
Q

when should cortisol be measured for indication of the function of the HPA axis?

A

9am

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14
Q

what can be measured to indicate GH hypersecretion?

A

IGF-1

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15
Q

what produces IGF-1?

A

the liver

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16
Q

what test should be done for suspected hormone excess?

A

suppression test

17
Q

what test should be done for suspected hormone deficiency?

A

stimulation test