Basics Flashcards
what are the three basic hormone subtypes?
proteins/peptides
amino acid derived
lipid derived
what is the most diverse class of hormones?
proteins and peptides
name three peptide hormones
insulin
GH
prolactin
name two amino acid derived hormones
adrenaline
melatonin
name two lipid derived hormone
testosterone
oestradiol
what is another name for lipid derived hormones?
steroid hormones
what type of receptor is the insulin receptor?
receptor tyrosine kinase activity
what type of receptor is the prolactin or growth hormone receptor?
cytokine receptor
what is the major determinant of hormone concentration?
rate of secretion
what is done to assess thyroid hormones?
highly sensitive TSH assay
what characterises sick euthyroid syndrome?
low free T3/4
inappropriate low/normal TSH
why is random cortisol measurement of little value?
secreted in a circadian pattern
when should cortisol be measured for indication of the function of the HPA axis?
9am
what can be measured to indicate GH hypersecretion?
IGF-1
what produces IGF-1?
the liver