population genetics & natural selection Flashcards
what evolves and what doesn’t?
population evolves but individuals don’t
what is a population?
localized group of individuals of the same species
what is a gene pool?
the total aggregate of genes (and their alleles) in the population at one time
Why might we need to estimate frequencies of genotypes in a population?
- To predict how many individuals will inherit a genetic disease
- To estimate the proportion of individuals who are ‘carriers’ of a genetic disease
How do we predict genotypes in a population?
Hardy-Weinberg equation
what is the allele frequency equation?
Allele frequency - p + q = 1
what is the allele frequency equation?
Allele frequency - p + q = 1
what is genotypic frequency equation?
Genotypic frequency - p2 + 2pq + q2 = 1
how can we predict genotypic frequency in a population?
through allele frequency
what are p and q in the Hardy-Weinberg equation?
p = frequency of dominant allele
q = frequency of recessive allele
what is pq in the Hardy-Weinberg equation?
heterozygous
what happens in an x-linked trait for females and males?
for an x-linked trait:
- females need to be homozygous recessive to get the disease
- males need just one recessive allele
what are ways allele frequency can change by?
- Non - random mating
- Random Genetic Drift
- Bottleneck Effect
- Founder Effect
- Natural Selection
- Gene Flow or Migration
- Mutation
what are two different types of nonrandom mating?
- assortative mating
- inbreeding
what is assortative mating?
attraction phenotype similar to your own