Polyomaviridae

Question 1

polyoma meaning

Answer 1

poly-many

oma-tumour

Question 2

morphology

Answer 2

circular dsDNA
icosahedral capsid
no envelope

Question 3

Does it have an envelope?

Answer 3

NO

Question 4

resistance

Answer 4

strong
56°C
 30 min
 pH 3
 lipid solvents

Question 5

Bio properties

Answer 5

Baltimore I. – cellular transcriptase

oncogenic – SV40 model virus

Question 6

Genus

Answer 6

Polyomavirus

Question 7

….borne?

Answer 7

airborne

Question 8

latency

Answer 8

integrates into genome-provirus

Question 9

causes

Answer 9

persistent infection of the kidney-viruria

Question 10

into cell cultures

Answer 10

microtumors

haemmaglutination

Question 11

diagnosis

Answer 11

IF, EM, HAI

NA-hybridization, PCR

Question 12

polyoma genus

Answer 12

Murine polyomavirus 
Simian polyomavirus SV40 
Bovine polyomavirus
Goose polyomavirus
Budgerigar fledgling disease virus
BK virus
JC virus

Question 13

Murine polyoma (A sp.)

Answer 13

lab mice

Question 14

Simian Polyoma (A sp.)

Answer 14

monkey-tumours, rondents

Question 15

Goose Polyoma (dis)

Answer 15

nephritis

Question 16

BK, JC virus (A sp.)

Answer 16

human

Question 17

BK virus (dis)

Answer 17

80-100% seropositivity
no clin symptoms or mild resp dis
nephropathy in kidney transplant patients

Question 18

JC virus (dis)

Answer 18

50-90% seroposivity
generally no clin signs
Progressive multifocal leucoencephalopathy