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Virology Final > Herpesviridae > Flashcards

Herpesviridae Flashcards

1
Q

Herpesvirus-meaning of the name

A

herpes-reptant, crawler

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2
Q

3 subfamilies

A

Alpha-, Beta-, Gamma-

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3
Q

Alphaherpesvirinae genuses

A

Simplex-, Varicello-, Mardi-, Iltovirus

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4
Q

Betaherpesvirinae genuses

A

Cytomegalo-, Muromegalo-, Porbosci-, Roseolovirus

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5
Q

Gammaherpesviridae genuses

A

Lymphocrypto-, Rhadino-, Maca-, Percavirus

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6
Q

The subfamilies differences

A

replication time (<>24)
latency sites
cytopathic effect

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7
Q

latency sites

A

ganglia, glands, macrophages, lymphocytes

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8
Q

cytopathic effects

A

inclusion bodies, cytomegaly, fusion

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9
Q

morphology

A

linear dsDNA
icosohedral capsid
enveloped

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10
Q

do they have an envelope

A

YES

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11
Q

resistance

A

pretty weak (detergents, heat)

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12
Q

latent infections

A

episoma, integration

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13
Q

strong CPE means

A

intranuclear inclusion bodies
syncytia
cell rounding, lysis

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14
Q

Oncogenicity?

A

mainly gamma

generally stenoxen

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15
Q

Antigenic properties

A

weak immunogens

cross reaction within genera

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16
Q

Cross reaction within genera

A

Aujeszky disease
EHV-1, EHV-4
Marek’s disease

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17
Q

diagnosis

A

isolation – cocultivation!
NA-hybridization, PCR
VN for identification

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18
Q

Simplex virus genus (sp.)

A

Bovine herpesmamillitis
Simian herpes
Human herpes simplex

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19
Q

Human herpes simplex (where and causes what)

A

labial and genital herpes

keartitis, encephalitis

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20
Q

Varicello virus genus (dis)

A 
infectious bovine rhinotracheitis
equine abortion/ rhinopneumonitis
coital exanthema
Aujeszky's /pseudorabies/
Canine herpes virus
Feline rhinotracheitis
Deer, reindeer, buffalo, monkey, seal herpesviruses
Human Varicella-Zoster
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21
Q

Infectious bovine rhinotracheitis (IBR)-symptoms

A

rhinotracheitis
abortion
IPV (infectious pustular vulvovaginitis)
IBP (balanopostitis)

22
Q

Aujeszky disease (pseudorabies)

A

SW: abortion, respiratory and CNS signs

lethal to other spp. with severe CNS signs

23
Q

Canine Herpesevirus

A

nasal and genital mucosa

puppy generalized

24
Q

Human varicella

A

chickenpox

25
Q

Varicella genus (spp)

A

EHP, BoHV, FeHP, CHP, HHV, SuHV

26
Q

Mardivirus genus (spp)

A

GaHV (turkey), MeHV

27
Q

Mardivirus genus (dis)

A

Marek’s disease

Turkey Herpesevirus

28
Q

Marek’s diesease symptoms

A

CNS signs
lymphatic tumours
paralysis

29
Q

Iltovirus genus (dis+spp)

A

Infectious laryngotracheitis - GaHV-1

30
Q

Cytomegalovirus genus (spp)

A

Human cytomegalovirus

Monkey cytomegaloviruses

31
Q

Muromegalovirus genus (spp)

A

Mouse, rat cytomegaloviruses

32
Q

Proboscivirus genus (spp)

A

Elephant cytomegalovirus

33
Q

Roseolovirus genus (spp+dis)

A

Human Roseola infectiosa-HHV 6,7

34
Q

Betaherpesvirinae (A sp)

A 
mouse
rat
elephant
human
monkey
35
Q

Lymphocriptovirus genus (spp)

A

Epstein-Barr virus (HHV-4)

Baboon, monkey, ape herpesviruses

36
Q

Epstein-Barr virus symptoms

A

Mononucleosis infectiosa
Burkitt’s lymphoma
nasopharyngeal carcinoma

37
Q

Lymphocryptovirus (A sp)

A

human, monnkey

38
Q

Macavirus genom (spp)

A

AlHV-1

OvHV-2

39
Q

Macavirus genom dis

A

malignant catarrhal fever of cattle

40
Q

Malignant catarrhal fever of cattle (symptoms)

A

wildebeest, sheep – asymptomatic carrier

cattle – oedema, erosions, pneumonia

41
Q

Macavirus genom (A sp)

A

cattle

sheep

42
Q

Pecavirus genum (spp)

A

Equid herpesvirus 2

Equid herpesvirus 5

43
Q

Equid herpesvirus 2 (symptoms)

A

foal pneumonia + Rh. equi

44
Q

Equid Herpesvirus 5 (symptoms)

A

pulmonary fibrosis

45
Q

Rhadinovirus genus (spp)

A

Bovine herpesvirus 4 (Movar)
Caposi Sarcoma-assotiated herpesvirus (HHV-8)
rodents, ruminants herpesvirus

46
Q

Pecavirus genum (A sp)

A

horses (foals)

47
Q

Rhadinovirus genus (A sp)

A

Rodents, cattle, human, ruminants

48
Q

Bovine herpesvirus 4 (Movar) (symptoms)

A

pneumonia

49
Q

Kaposi’s sarcoma-associated herpesvirus

A

human, in immunosuppressant patients

50
Q

unassigned herpesviruses

A

Swine inclusion body rhinitis (SuHV-2)
Duck plague (AnHV-1)
Pigeon herpes
Pacheco’s disease

51
Q

Pacheco’s disease

A

parrot hepatitis

52
Q

Alloherpesvirus genus

A

Koi herpes – carp

Sturgeon, salmon herpesviruses

Virology Final (18 decks)

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