Herpesviridae

Question 1

Herpesvirus-meaning of the name

Answer 1

herpes-reptant, crawler

Question 2

3 subfamilies

Answer 2

Alpha-, Beta-, Gamma-

Question 3

Alphaherpesvirinae genuses

Answer 3

Simplex-, Varicello-, Mardi-, Iltovirus

Question 4

Betaherpesvirinae genuses

Answer 4

Cytomegalo-, Muromegalo-, Porbosci-, Roseolovirus

Question 5

Gammaherpesviridae genuses

Answer 5

Lymphocrypto-, Rhadino-, Maca-, Percavirus

Question 6

The subfamilies differences

Answer 6

replication time (<>24)
latency sites
cytopathic effect

Question 7

latency sites

Answer 7

ganglia, glands, macrophages, lymphocytes

Question 8

cytopathic effects

Answer 8

inclusion bodies, cytomegaly, fusion

Question 9

morphology

Answer 9

linear dsDNA
icosohedral capsid
enveloped

Question 10

do they have an envelope

Answer 10

YES

Question 11

resistance

Answer 11

pretty weak (detergents, heat)

Question 12

latent infections

Answer 12

episoma, integration

Question 13

strong CPE means

Answer 13

intranuclear inclusion bodies
syncytia
cell rounding, lysis

Question 14

Oncogenicity?

Answer 14

mainly gamma

generally stenoxen

Question 15

Antigenic properties

Answer 15

weak immunogens

cross reaction within genera

Question 16

Cross reaction within genera

Answer 16

Aujeszky disease
EHV-1, EHV-4
Marek’s disease

Question 17

diagnosis

Answer 17

isolation – cocultivation!
NA-hybridization, PCR
VN for identification

Question 18

Simplex virus genus (sp.)

Answer 18

Bovine herpesmamillitis
Simian herpes
Human herpes simplex

Question 19

Human herpes simplex (where and causes what)

Answer 19

labial and genital herpes

keartitis, encephalitis

Question 20

Varicello virus genus (dis)

Answer 20

infectious bovine rhinotracheitis
equine abortion/ rhinopneumonitis
coital exanthema
Aujeszky's /pseudorabies/
Canine herpes virus
Feline rhinotracheitis
Deer, reindeer, buffalo, monkey, seal herpesviruses
Human Varicella-Zoster

Question 21

Infectious bovine rhinotracheitis (IBR)-symptoms

Answer 21

rhinotracheitis
abortion
IPV (infectious pustular vulvovaginitis)
IBP (balanopostitis)

Question 22

Aujeszky disease (pseudorabies)

Answer 22

SW: abortion, respiratory and CNS signs

lethal to other spp. with severe CNS signs

Question 23

Canine Herpesevirus

Answer 23

nasal and genital mucosa

puppy generalized

Question 24

Human varicella

Answer 24

chickenpox

Question 25

Varicella genus (spp)

Answer 25

EHP, BoHV, FeHP, CHP, HHV, SuHV

Question 26

Mardivirus genus (spp)

Answer 26

GaHV (turkey), MeHV

Question 27

Mardivirus genus (dis)

Answer 27

Marek's disease | Turkey Herpesevirus

Question 28

Marek's diesease symptoms

Answer 28

CNS signs lymphatic tumours paralysis

Question 29

Iltovirus genus (dis+spp)

Answer 29

Infectious laryngotracheitis - GaHV-1

Question 30

Cytomegalovirus genus (spp)

Answer 30

Human cytomegalovirus | Monkey cytomegaloviruses

Question 31

Muromegalovirus genus (spp)

Answer 31

Mouse, rat cytomegaloviruses

Question 32

Proboscivirus genus (spp)

Answer 32

Elephant cytomegalovirus

Question 33

Roseolovirus genus (spp+dis)

Answer 33

Human Roseola infectiosa-HHV 6,7

Question 34

Betaherpesvirinae (A sp)

Answer 34

``` mouse rat elephant human monkey ```

Question 35

Lymphocriptovirus genus (spp)

Answer 35

Epstein-Barr virus (HHV-4) | Baboon, monkey, ape herpesviruses

Question 36

Epstein-Barr virus symptoms

Answer 36

Mononucleosis infectiosa Burkitt's lymphoma nasopharyngeal carcinoma

Question 37

Lymphocryptovirus (A sp)

Answer 37

human, monnkey

Question 38

Macavirus genom (spp)

Answer 38

AlHV-1 | OvHV-2

Question 39

Macavirus genom dis

Answer 39

malignant catarrhal fever of cattle

Question 40

Malignant catarrhal fever of cattle (symptoms)

Answer 40

wildebeest, sheep – asymptomatic carrier | cattle – oedema, erosions, pneumonia

Question 41

Macavirus genom (A sp)

Answer 41

cattle | sheep

Question 42

Pecavirus genum (spp)

Answer 42

Equid herpesvirus 2 | Equid herpesvirus 5

Question 43

Equid herpesvirus 2 (symptoms)

Answer 43

foal pneumonia + Rh. equi

Question 44

Equid Herpesvirus 5 (symptoms)

Answer 44

pulmonary fibrosis

Question 45

Rhadinovirus genus (spp)

Answer 45

Bovine herpesvirus 4 (Movar) Caposi Sarcoma-assotiated herpesvirus (HHV-8) rodents, ruminants herpesvirus

Question 46

Pecavirus genum (A sp)

Answer 46

horses (foals)

Question 47

Rhadinovirus genus (A sp)

Answer 47

Rodents, cattle, human, ruminants

Question 48

Bovine herpesvirus 4 (Movar) (symptoms)

Answer 48

pneumonia

Question 49

Kaposi’s sarcoma-associated herpesvirus

Answer 49

human, in immunosuppressant patients

Question 50

unassigned herpesviruses

Answer 50

Swine inclusion body rhinitis (SuHV-2) Duck plague (AnHV-1) Pigeon herpes Pacheco’s disease

Question 51

Pacheco's disease

Answer 51

parrot hepatitis

Question 52

Alloherpesvirus genus

Answer 52

Koi herpes – carp | Sturgeon, salmon herpesviruses