Papillomaviridae Flashcards

1
Q

Papiloma meaning

A

papila-wart (verrue)

oma-tumour

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2
Q

morphology

A

circular dsDNA-superhelical
icosohedral capsid
no capsule

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3
Q

Does it have a capsule?

A

NO

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4
Q

resistance

A

strong
56°C, 30 min;
pH 3
lipid solvents

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5
Q

Bio properties

A

Baltimore I. – cellular transcriptase

virus assembly in keratinized cells

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6
Q

This virus has restricted host range, predilection sites

What do we call this?

A

stenoxen

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7
Q

Causes?

A

beningnant tumours (oncogenic)

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8
Q

Latency

A

episomal DNA

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9
Q

Transmition

A

contact, veneral transmition-cell associated

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10
Q

Antigenic properties

A

good Ag properties
hiddden from the immune system
no cross reaction
autovaccine

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11
Q

diagnosis

A

clin signs
IF, IM
NA hybridization

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12
Q

Papiloma genus (dis)

A

Equine, bovine papillomatosis
Canine oral papillomatosis
Skin papillomas
Genital papillomas

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13
Q

Equine papillomatosis

A

head, nose

transmition by bite, twitch

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14
Q

Bovine papillomatosis

A

1-13
neck, back, body
horse sarcoid

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15
Q

Canine oral papillomatosis

A

oral mucosa

epulis (cancer like enlargement on the alveolar lucosa or gingiva)

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16
Q

Affected spicies

A

HORSE, CATTLE, DOG, sheep, roe deer, elephant, elk (wapiti), possum, rabbit, turttle, parrot, HUMAN

17
Q

Skin papilloma

A

human (1-63)
veruca vulgaris
squamosus cell carcinomas

18
Q

Genital papillomas

A
human (1-63)
sexually transmitted
Juvenile laryngeal carcinomas 
Cervical intraepithelial neoplasia
Vulval-, penile carcinomas